Methyl 3-aMino-2-chlorobenzoate
- Product Name
- Methyl 3-aMino-2-chlorobenzoate
- CAS No.
- 120100-15-4
- Chemical Name
- Methyl 3-aMino-2-chlorobenzoate
- Synonyms
- Methyl 3-aMino-2-chlorobenzoate;Benzoic acid, 3-amino-2-chloro-, methyl ester
- CBNumber
- CB32595260
- Molecular Formula
- C8H8ClNO2
- Formula Weight
- 185.61
- MOL File
- 120100-15-4.mol
Methyl 3-aMino-2-chlorobenzoate Property
- Boiling point:
- 298.5±20.0 °C(Predicted)
- Density
- 1.311±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 1.51±0.10(Predicted)
- Appearance
- Brown to reddish brown Liquid
N-Bromosuccinimide Price
- Product number
- 7385CV
- Product name
- Methyl3-amino-2-chlorobenzoate
- Packaging
- 100mg
- Price
- $149
- Updated
- 2021/12/16
- Product number
- CM130935
- Product name
- methyl3-amino-2-chlorobenzoate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $246
- Updated
- 2021/12/16
- Product number
- CD12174300
- Product name
- Methyl3-amino-2-chlorobenzoate
- Purity
- 97%
- Packaging
- 1g
- Price
- $260
- Updated
- 2021/12/16
- Product number
- AN008774
- Product name
- Methyl3-amino-2-chlorobenzoate
- Purity
- 95%
- Packaging
- 1gm:
- Price
- $296.9
- Updated
- 2021/12/16
- Product number
- 61-10449
- Product name
- Methyl3-amino-2-chlorobenzoate
- Purity
- 95-98%
- Packaging
- 1g
- Price
- $315
- Updated
- 2021/12/16
Methyl 3-aMino-2-chlorobenzoate Chemical Properties,Usage,Production
Synthesis
53553-14-3
120100-15-4
Step B: Synthesis of methyl 3-amino-2-chlorobenzoate; Raney Ni catalyst (3 g) was added to a methanol (MeOH, 150 mL) solution of methyl 2-chloro-3-nitrobenzoate (25 g, 116 mmol). The reaction mixture was placed under hydrogen atmosphere (50 psi, 25 °C) and stirred for 3.5 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to dryness under reduced pressure to give the crude product. The crude product was purified by recrystallization from ethyl acetate (EtOAc) to afford the title compound methyl 3-amino-2-chlorobenzoate (four batches were combined with a total yield of 69 g in 83.5% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 6.7-7.5.25 (m, 3H, aryl H), 4.40-4.50 (br, 2H, NH2), 3.87 (s, 3H, OCH3).
References
[1] Patent: JP2015/528022, 2015, A. Location in patent: Paragraph 0659
[2] Patent: WO2018/134254, 2018, A1. Location in patent: Page/Page column 64; 65
[3] Patent: US2009/298815, 2009, A1. Location in patent: Page/Page column 63
[4] Patent: WO2011/59610, 2011, A1. Location in patent: Page/Page column 97
[5] Patent: US6177440, 2001, B1
Methyl 3-aMino-2-chlorobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 3-aMino-2-chlorobenzoate Suppliers
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