TPPB

Product Name: TPPB
CAS No.: 497259-23-1
Chemical Name: TPPB
Synonyms: TPPB;CS-2585;TPPB, 10 mM in DMSO;α-Amyloid Precursor Protein Modulator;alpha-AMyloid Precursor Protein Modulator;PKC,Protein kinase C,TPPB,inhibit,Inhibitor;α-Amyloid Precursor Protein Modulator(TPPB);α-Amyloid Precursor Protein Modulator, >=98%;TPPB/ α-Amyloid Precursor Protein Modulator;(2E,4E)-N-[(2S,5R)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1-benzazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide
CBNumber: CB32602544
Molecular Formula: C27H30F3N3O3
Formula Weight: 501.54
MOL File: 497259-23-1.mol

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TPPB Property

Boiling point:: 728.8±60.0 °C(Predicted)
Density: 1.229
storage temp.: Store at -20°C
solubility: 25.08mg/mL in DMSO
pka: 12.76±0.60(Predicted)
form: Solid
color: Light yellow to yellow
InChIKey: WOLVEMPZUIFSII-IHHOKICGSA-N
SMILES: C(NC1=CC=C2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CC2=C1)(=O)/C=C/C=C/C1=CC=C(C(F)(F)F)C=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 565740
Product name: α-Amyloid Precursor Protein Modulator
Purity: A cell-permeable benzolactam derived PKC activator (K<sub>i</sub> = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100
Packaging: 1 mg
Price: $359
Updated: 2025/07/31

Tocris

Product number: 5343
Product name: TPPB
Purity: ≥98%(HPLC)
Packaging: 1
Price: $145
Updated: 2021/12/16

TRC

Product number: T700578
Product name: TPPB
Packaging: 1mg
Price: $285
Updated: 2021/12/16

TRC

Product number: T700578
Product name: TPPB
Packaging: 2.5mg
Price: $615
Updated: 2021/12/16

ChemScene

Product number: CS-7939
Product name: TPPB
Purity: 99.81%
Packaging: 1mg
Price: $200
Updated: 2021/12/16

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TPPB Chemical Properties,Usage,Production

Uses

TPPB is a protein kinase C (PKC) activator.

Biological Activity

Cell permeable: yes', 'Primary Target
PKC', 'Product does not compete with ATP.', 'Reversible: no', 'Target Ki: 11.9 nM for activating PKCα

storage

Store at -20°C

TPPB Preparation Products And Raw materials

Raw materials

Preparation Products

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TPPB Suppliers

China 82 United Kingdom 1 United States 13 Global 96

Changsha Fuzhen Biotechnology Co.，LTD

Tel: 0731-13823398 15111215862
Email: 313359644@qq.com
Country: China
ProdList: 4161
Advantage: 58

Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd

Tel: 15317229551
Fax: QQ:3607245178
Email: 15151849396@163.com
Country: China
ProdList: 989
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chengdu NoVi Biotechnology Co., Ltd.

Tel: 028-81458053
Fax: 028-81458053
Email: novibiotech@163.com sales@novi-biotech.com
Country: China
ProdList: 226
Advantage: 55

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Twochem Co.Ltd

Tel: 021-021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 304
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Lancrix Chemicals

Tel: 86-21-50817262
Fax: 86-21-57712035
Email: sales@lancrix.com
Country: China
ProdList: 1502
Advantage: 55

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View Lastest Price from TPPB manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: TPPB 497259-23-1
Price: US $0.00-0.00/KG
Min. Order: 10mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-17

497259-23-1, TPPBRelated Search:

TPPB

(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide

alpha-AMyloid Precursor Protein Modulator

TPPB/ α-Amyloid Precursor Protein Modulator

α-Amyloid Precursor Protein Modulator, >=98%

(2E,4E)-N-((2S,5S)-5-(hydroxymethyl)-2-isopropyl-1-methyl-3-oxo-1,2,3,4,5,6-hexahydrobenzo[e][1,4]diazocin-8-yl)-5-(4-(trifluoromethyl)phenyl)penta-2,4-dienamide

(2E,4E)-N-[(2S,5R)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1-benzazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide

CS-2585

2,4-Pentadienamide, N-[(2S,5S)-1,2,3,4,5,6-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-, (2E,4E)-

α-Amyloid Precursor Protein Modulator

PKC,Protein kinase C,TPPB,inhibit,Inhibitor

(2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide

α-Amyloid Precursor Protein Modulator(TPPB)

(2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide

TPPB, 10 mM in DMSO

497259-23-1

C27H30F3N3O3

C28H31F3N2O3

API