N-(3,5-DiMethyladaMantan-1-yl)forMaMide

Product Name: N-(3,5-DiMethyladaMantan-1-yl)forMaMide
CAS No.: 351329-88-9
Chemical Name: N-(3,5-DiMethyladaMantan-1-yl)forMaMide
Synonyms: N-ForMyl MeMantine;Memantine USP RC E;MeMantine Related CoMpound E; Adamantane Impurity E;Memantine USP impurity E;Memantine Related Compound 2;N-(3,5-DiMethyladaMantan-1-yl);Memantine USP Related Compound E;1-ForMylaMino-3,5-diMethyladaMantane;N-(3,5-dimethyl-1-adamantyl)formamide
CBNumber: CB32622883
Molecular Formula: C13H21NO
Formula Weight: 207.31
MOL File: 351329-88-9.mol

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N-(3,5-DiMethyladaMantan-1-yl)forMaMide Property

Melting point:: 69.5℃
Boiling point:: 325.6±9.0 °C(Predicted)
Density: 1.07±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 16.08±0.60(Predicted)
color: White to Off-White
InChI: InChI=1S/C13H21NO/c1-11-3-10-4-12(2,6-11)8-13(5-10,7-11)14-9-15/h9-10H,3-8H2,1-2H3,(H,14,15)
InChIKey: NYQWYYMEIBHRSB-UHFFFAOYSA-N
SMILES: C(NC12CC3(C)CC(CC(C)(C3)C1)C2)=O

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Safety

HS Code: 2903890002

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: F700740
Product name: N-FormylMemantine
Packaging: 50mg
Price: $100
Updated: 2021/12/16

TRC

Product number: F700740
Product name: N-FormylMemantine
Packaging: 100mg
Price: $125
Updated: 2021/12/16

ChemScene

Product number: CS-0061413
Product name: N-(3,5-Dimethyl-1-adamantyl)formamide
Purity: 99.64%
Packaging: 100mg
Price: $59
Updated: 2021/12/16

ChemScene

Product number: CS-0061413
Product name: N-(3,5-Dimethyl-1-adamantyl)formamide
Purity: 99.64%
Packaging: 250mg
Price: $114
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD57647
Product name: N-3,5-Dimethyladamantan-1-yl formamide
Packaging: 25mg
Price: $120
Updated: 2021/12/16

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N-(3,5-DiMethyladaMantan-1-yl)forMaMide Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

N-Formyl Memantine is an impurity of Memantine (M218000). Memantine impurity E per USP.

Synthesis

941-37-7

77287-34-4

351329-88-9

GENERAL METHOD: To a 17 mL stainless steel pressure microreactor or glass vial under argon protection, 0.3 mmol of manganese-containing catalyst, 10 mmol of 1-bromo-3,5-dimethyladamantane (I), and 30 mmol of formamide were sequentially added. The reaction mixture was heated with stirring at 120-130°C for 3-4 hours. After completion of the reaction, the reactor was cooled to room temperature and opened. The reaction mixture was washed with water and the reaction product was subsequently extracted with 33 mL of dichloromethane. The solvent was removed by distillation under reduced pressure and the residue was purified by recrystallization. Further purification by silica gel column chromatography (eluent: hexane-ethyl acetate mixed solvent) afforded N-(3,5-dimethyladamantan-1-yl)formamide (II). The yield of the product was 78% and the melting point was 69-70°C (hexane recrystallization). Its physicochemical properties and NMR spectral data were in agreement with those reported in the literature [7].

References

[1] Russian Journal of General Chemistry, 2015, vol. 85, # 7, p. 1771 - 1772
[2] Zh. Obshch. Khim., 2015, vol. 85, # 7, p. 1210 - 1211,2
[3] Patent: WO2010/15415, 2010, A1. Location in patent: Page/Page column 16-17
[4] Patent: WO2010/83996, 2010, A1. Location in patent: Page/Page column 20-21

N-(3,5-DiMethyladaMantan-1-yl)forMaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(3,5-DiMethyladaMantan-1-yl)forMaMide Suppliers

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View Lastest Price from N-(3,5-DiMethyladaMantan-1-yl)forMaMide manufacturers

Wuhan Boye Science And Technology Development Co., Ltd.

Product: N-(3,5-DiMethyladaMantan-1-yl)forMaMide 351329-88-9
Price: US $0.00/ASSAYS
Min. Order: 100ASSAYS
Purity: 98%
Supply Ability: 1tons
Release date: 2021-04-25

Career Henan Chemical Co

Product: N-(3,5-DiMethyladaMantan-1-yl)forMaMide 351329-88-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-18

351329-88-9, N-(3,5-DiMethyladaMantan-1-yl)forMaMideRelated Search:

Memantine Related Compound 1 Memantine-glucose Adduct 1 1-Bromo-3,5-dimethyladamantane 3-AMINO-5,7-DIMETHYLADAMANTAN-1-OL Hydrochloride Memantine-Galactose Adduct 1 1-Actamido-3,5-dimethyladmantane Memantine Glucuronic Acid Conjugate (Furanose Form) 3,5-DiMethyl-1-nitroadaMantane Tricyclo[3.3.1.13,7]decan-1-aMine, 3,5,7-triMethyl-, hydrochloride Memantine Lactose Adduct Demethyl Memantine Hydrochloride Memantine

1-ForMylaMino-3,5-diMethyladaMantane

N-(3,5-DiMethyladaMantan-1-yl)forMaMide

N-(3,5-DiMethyltricyclo[3.3.1.13,7]dec-1-yl)forMaMide

N-ForMyl MeMantine

Memantine USP Related Compound E

Memantine Related Compound E (15 mg) (N-3,5-Dimethyladamantan-1-yl formamide)

Memantine USP RC E

MeMantine Related CoMpound E

Memantine Impurity 5(Memantine USP RC E)

N-(3,5-dimethyl-1-adamantyl)formamide

N-(3,5-DiMethyladaMantan-1-yl)

FORMAMIDE, N-(3,5-DIMETHYLTRICYCLO[3.3.1.13,7]DEC-1-YL)-

N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)formamide

Memantine Related Compund E (N-3,5-Dimethyladamantan-1-yl formamide)

Adamantane Impurity E

Memantine Impurity EQ: What is Memantine Impurity E Q: What is the CAS Number of Memantine Impurity E Q: What is the storage condition of Memantine Impurity E Q: What are the applications of Memantine Impurity E

Memantine Related Compound E (N-3,5-Dimethyladamantan-1-yl formamide) (1380557)

Memantine Related Compound 2

Piperidine,1-(3-chloropropyl)-,hydrochloride(1:3)

Memantine Related Compound E N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)formamide

Memantine USP impurity E

N-(3,5-Dimethyladamantan-1-yl)formamide,98%

351329-88-9

351329-77-8

Amines

Impurities

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