1-Actamido-3,5-dimethyladmantane

Product Name: 1-Actamido-3,5-dimethyladmantane
CAS No.: 19982-07-1
Chemical Name: 1-Actamido-3,5-dimethyladmantane
Synonyms: Acetyl memantine;Memantine N-Acetyl;N-Acetyl Memantine ;MeMantine IMpurity C;Memantine impurity E;Memantine Acetyl Impurity;Memantine Related Compound F;Memantine Impurity C (N-Acetyl;1-actamido-3,5-dimethyladmantane;1-ACETAMIDO-3,5-DIMETHYLADMANTANE
CBNumber: CB3855230
Molecular Formula: C14H23NO
Formula Weight: 221.34
MOL File: 19982-07-1.mol

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1-Actamido-3,5-dimethyladmantane Property

Melting point:: 110-111°C
Boiling point:: 348.5±9.0 °C(Predicted)
Density: 1.05
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
pka: 16.20±0.60(Predicted)
form: Solid
color: White
CAS DataBase Reference: 19982-07-1(CAS DataBase Reference)

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Safety

HS Code: 2902190000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2653
Product name: N-Acetyl-3,5-dimethyl-1-adamantanamine
Purity: >97.0%(GC)
Packaging: 1g
Price: $208
Updated: 2025/07/31

TCI Chemical

Product number: A2653
Product name: N-Acetyl-3,5-dimethyl-1-adamantanamine
Purity: >97.0%(GC)
Packaging: 5g
Price: $734
Updated: 2025/07/31

Biosynth Carbosynth

Product number: IA11847
Product name: N-Acetylmemantine
Packaging: 500mg
Price: $40
Updated: 2021/12/16

Biosynth Carbosynth

Product number: IA11847
Product name: N-Acetylmemantine
Packaging: 1g
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: IA11847
Product name: N-Acetylmemantine
Packaging: 2g
Price: $100
Updated: 2021/12/16

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1-Actamido-3,5-dimethyladmantane Chemical Properties,Usage,Production

Chemical Properties

1-Actamido-3,5-dimethyladmantane is White Solid

Uses

1-Actamido-3,5-dimethyladmantane is an intermediate used for preparation of Memantine (M218000).

Synthesis

707-37-9

75-05-8

19982-07-1

[0063] 1.00 g (5.50 mmol) of 3,5-dimethyl-1-adamantanol, 0.46 g (11.1 mmol) of acetonitrile, and 9.61 g of homotrimethylbenzene were added to a test tube with an outer diameter of 30 mm and mixed well. Subsequently, 1.12 g (11.1 mmol) of 97% concentrated sulfuric acid was slowly added dropwise to the mixed solution in the test tube to form a reaction solution. The reaction solution was stirred at a constant temperature at 30°C for 3 hours to promote the reaction. Upon completion of the reaction, 6.09 g of water was added to the reaction solution to quench the reaction, and the aqueous phase was removed by aqueous washing to obtain a homotrimethylbenzene solution containing 1-acetamido-3,5-dimethyladamantane (reaction yield: 80.4%). Next, 0.71 g of sodium hydroxide hydrate and 9.61 g of 1-hexanol were added to this solution to prepare a reaction solution. The reaction solution was stirred at 130 °C for 18 h to achieve hydrolysis of 1-acetamido-3,5-dimethyladamantane. Finally, the reaction solution was analyzed by gas chromatography (GC) to confirm the generation of memantine (reaction yield: 96.2%).

References

[1] Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, p. 867 - 871
[2] Zhurnal Organicheskoi Khimii, 1982, vol. 18, # 5, p. 1001 - 1005
[3] Patent: EP2949643, 2015, A1. Location in patent: Paragraph 0063

1-Actamido-3,5-dimethyladmantane Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Actamido-3,5-dimethyladmantane Suppliers

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View Lastest Price from 1-Actamido-3,5-dimethyladmantane manufacturers

Dideu Industries Group Limited

Product: 1-Actamido-3,5-dimethyladmantane 19982-07-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2025-09-19

Wuhan JiyunZen Tech Co., Ltd.

Product: 1-Actamido-3,5-dimethyladmantane 19982-07-1
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-05-30

Henan Aochuang Chemical Co.,Ltd.

Product: 1-Actamido-3,5-dimethyladmantane 19982-07-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-12

19982-07-1, 1-Actamido-3,5-dimethyladmantaneRelated Search:

ETHANE Dacthal Dimethyl fumarate Dimethyl carbonate Dimethyl sulfate Dimethyl sulfoxide Acetamide Acetaminophen N,N-Dimethylformamide Dimethyl ether Dimethyl phthalate 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride Tricyclo[3.3.1.13,7]decan-1-aMine, 3,5,7-triMethyl-, hydrochloride 3-AMINO-5,7-DIMETHYLADAMANTAN-1-OL Hydrochloride Memantine Lactose Adduct Memantine Related Compound 1 Adamantane 1-Actamido-3,5-dimethyladmantane

n-(3,5-dimethyl-1-adamantyl)-acetamide

1-ACETAMIDO-3,5-DIMETHYLADMANTANE

1-Acetamido-3,5-dimethyladamantane

1-acetate amino-3，5- Dimethyl Adamantane

1. 1-actamido-3,5-dimethyladmantane

N-Acetyl Memantine

AcetylaMino-3,5-diMethyladaMantane

Acetamide,N-(3,5-dimethyltricyclo[3.3.1.13,7]dec-1-yl)-

N-Acetyl-3,5-diMethyl-1-adaMantanaMine

1-actamido-3,5-dimethyladmantane

N-(3,5-DiMethyltricyclo[3.3.1.13,7]dec-1-yl)acetaMide

1-N-AcetylaMino-3,5-diMethyladaMantane

N-(3,5-diMethyladaMantan-1-yl)acetaMide

MeMantine IMpurity C

<i>N</i>-Acetyl-3,5-dimethyl-1-adamantanamine

Memantine impurity E

N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

1-Actamido-3,5-dimethyladamantane

Memantine Acetyl Impurity

Acetyl memantine

Memantine Impurity 14(N-Acetyl Memantine)

Memantine Impurity C (N-Acetyl Memantine)

N-Acetyl-3,5-dimethyl-1-adamantanamine &gt

Memantine Related Compound F

Memantine N-Acetyl

Memantine Impurity C (N-Acetyl

Memantine Impurity 1 (N-Acetyl Memantine)

N-Acetyl-3,5-dimethyl-1-adamantanamine, ≥ 97.0%

Memantine Hydrochloride Impurity C

1-Acylamino-3,5-dimethyladamantane

19982-07-1

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