GUANABENZ
- Product Name
- GUANABENZ
- CAS No.
- 5051-62-7
- Chemical Name
- GUANABENZ
- Synonyms
- Rexitene;GUANABENZ;nsc-68982;Callosum benzyl;GUANABENZ USP/EP/BP;Guanabenz (WY 8678);GUANABENZ, 10 mM in DMSO;1-(2,6-DICHLOROBENZYLIDENEAMINO)GUANIDINE;n-(2,6-dichlorobenzylidene)amino]guanidine;n-(2,6-dichlorobenzylidene)-n’-amidinohydrazine
- CBNumber
- CB3263851
- Molecular Formula
- C8H8Cl2N4
- Formula Weight
- 231.08
- MOL File
- 5051-62-7.mol
GUANABENZ Property
- Melting point:
- 227-229° (dec)
- Boiling point:
- 353.9±52.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 12 mg/mL (51.93 mM);Ethanol: 15 mg/mL (64.91 mM)
- pka
- pKa 8.1 (Uncertain)
- Water Solubility
- Water: Insoluble
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-62
- Safety Statements
- 22-36/37/39
- RIDADR
- 3249
- WGK Germany
- 3
- HazardClass
- 6.1(b)
- PackingGroup
- III
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P281Use personal protective equipment as required.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S762091
- Product name
- N-(2,6-DICHLOROBENZYLIDENEAMINO)GUANIDINE
- Purity
- Aldrich
- Packaging
- 50mg
- Price
- $179
- Updated
- 2024/03/01
- Product number
- API0006231
- Product name
- GUANABENZ
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.68
- Updated
- 2021/12/16
- Product number
- 75138
- Product name
- Guanabenz
- Packaging
- 5mg
- Price
- $1545
- Updated
- 2021/12/16
- Product number
- CSN23785
- Product name
- GUANABENZ
- Packaging
- 100mg
- Price
- $237
- Updated
- 2021/12/16
- Product number
- MT-08425
- Product name
- 1-(2,6-Dichlorobenzylideneamino)guanidine
- Purity
- 98%
- Packaging
- 0.1g
- Price
- $306
- Updated
- 2021/12/16
GUANABENZ Chemical Properties,Usage,Production
Description
Guanabenz is an α2-adrenergic agonist that exhibits pronounced hypotensive action, and that is associated with a reduction of overall peripheral vascular resistance, decline in frequency of cardiac contractions, and reduced cardiac output.
Originator
Wytensin,Wyeth,US,1982
Uses
alpha agonists
Uses
It is used both independently and in combination with oral diuretics for treating various degrees of hypertension.
Definition
ChEBI: Guanabenz is a dichlorobenzene.
Manufacturing Process
A mixture of 14.0 g of 2,6-dichlorobenzaldehyde, 10.8 g of aminoguanidine bicarbonate and 100 ml of pyridine was refluxed for 3 hours. The reaction mixture was poured into water and the crystalline precipitate filtered off; MP 225°C to 227°C.
Therapeutic Function
Antihypertensive
Synthesis
Guanabenz, [(2,6-dichlorobenzyliden) amino] guanidine (22.3.1), is synthesized in one step by reacting 2,6-dichlorobenzaldehyde with amino guanidine.
Purification Methods
Crystallise the guanidine from MeCN and store it in a CO2–free atmosphere. The monoHCl [23256-5-0] has m 178o(dec) [solubility w% at 25o is 1.1(H2O), 5(EtOH), 0.1(EtOAc), 0.06(CHCl3)]. It is an antihypertensive drug. [Holmes et al. Drugs 26 212 1983.]
GUANABENZ Preparation Products And Raw materials
Raw materials
Preparation Products
GUANABENZ Suppliers
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10266
- Advantage
- 58
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12335
- Advantage
- 58
- Tel
- 021-33632979
- Fax
- 021-34692979
- info@tsbiochem.com
- Country
- China
- ProdList
- 8065
- Advantage
- 58
- Tel
- 18149758185 18149758185
- sales-cpd@caerulumpharma.com
- Country
- China
- ProdList
- 3466
- Advantage
- 58
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9648
- Advantage
- 58
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 13621943973
- Fax
- -
- sales@shjiyipharmatech.com
- Country
- China
- ProdList
- 1166
- Advantage
- 55
- Tel
- 17754423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8011
- Advantage
- 62
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 7312
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- +86-27-87465837 +8618971612321
- Fax
- 86 27 87772287
- info@finetechnology-ind.com
- Country
- China
- ProdList
- 9639
- Advantage
- 58
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
- Country
- China
- ProdList
- 22787
- Advantage
- 58
- Tel
- +86-0571-85134551
- Fax
- 008657185134895
- sales@afinechem.com
- Country
- China
- ProdList
- 15352
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30233
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9409
- Advantage
- 58
- Tel
- 13621943973; 13621943973
- sales@jamxmpharmatech.com
- Country
- China
- ProdList
- 1114
- Advantage
- 58
- Tel
- 021-51111890 15317326293
- sales@molnova.com
- Country
- China
- ProdList
- 4195
- Advantage
- 58
- Tel
- 18252089365
- Krain_kerun@163.com
- Country
- China
- ProdList
- 2615
- Advantage
- 58
- Tel
- 13348960310 13348960310
- 3003867561@qq.com
- Country
- China
- ProdList
- 10524
- Advantage
- 58
- Tel
- 15865264761
- 486064515@qq.com
- Country
- China
- ProdList
- 4996
- Advantage
- 58
- Tel
- 18902340307 18902340307
- Fax
- 0751-2819901
- 3356812514@qq.com
- Country
- China
- ProdList
- 9244
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 62075
- Advantage
- 58
- Tel
- 029-029-81148696 18161915376
- 1040@dideu.com
- Country
- China
- ProdList
- 9997
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24644
- Advantage
- 58
- Tel
- 0751-2818792 13435114148
- 3128240096@qq.com
- Country
- China
- ProdList
- 2988
- Advantage
- 58
- Tel
- 13417589054 13417589054
- trendseenbio@gmail.com
- Country
- China
- ProdList
- 9070
- Advantage
- 58
- Tel
- 400-400-8210725 17717813675;
- malulu@leyan.com
- Country
- China
- ProdList
- 39988
- Advantage
- 58
- Tel
- 025-58851786 17714337195
- sales@tybiochem.com
- Country
- China
- ProdList
- 6827
- Advantage
- 58
- Tel
- 021-57520305 15801958784
- lihua@jskchem.com
- Country
- China
- ProdList
- 49234
- Advantage
- 58
- Tel
- 021-54306202 18917919676
- info@hanhongsci.com
- Country
- China
- ProdList
- 29979
- Advantage
- 58
- Tel
- 13356901049
- 1701654643@qq.com
- Country
- China
- ProdList
- 9273
- Advantage
- 58
- Tel
- 025-85560043 15850508050
- Fax
- 025-85563444
- cindy.huang@synzest.com
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 400-6206333 18021050169
- market@aladdin-e.com
- Country
- China
- ProdList
- 48461
- Advantage
- 58
- Tel
- 025-66061636 18013972705
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 10238
- Advantage
- 58
- Tel
- 18122215013
- 780229652@qq.com
- Country
- China
- ProdList
- 1233
- Advantage
- 58
- Tel
- sangon@qq.com
- Country
- CHINA
- ProdList
- 47239
- Advantage
- 58
- Tel
- +undefined-21-51877795
- Fax
- +86 21 5161 9052/ 5187 7796
- ivan@atkchemical.com
- Country
- China
- ProdList
- 32965
- Advantage
- 60
- Tel
- 13417589054
- trendseenbio@gmail.com
- Country
- China
- ProdList
- 11681
- Advantage
- 58
- Tel
- +8618058761490
- info@gihichemicals.com
- Country
- China
- ProdList
- 49982
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@biorbyt.com
- Country
- CHINA
- ProdList
- 6579
- Advantage
- 58
- Tel
- --
- Fax
- --
- chenjw@absin.cn
- Country
- CHINA
- ProdList
- 6705
- Advantage
- 58
- Tel
- --
- Fax
- --
- Proteintech-CN@ptglab.com
- Country
- CHINA
- ProdList
- 6290
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@lanospharma.com
- Country
- China
- ProdList
- 6329
- Advantage
- 56
- Tel
- --
- Fax
- --
- weibochem@163.com
- Country
- China
- ProdList
- 6187
- Advantage
- 67
View Lastest Price from GUANABENZ manufacturers
- Product
- GUANABENZ 5051-62-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-10
- Product
- Guanabenz 5051-62-7
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-09