trans/cis Resveratrol-D4
- Product Name
- trans/cis Resveratrol-D4
- CAS No.
- 1089051-56-8
- Chemical Name
- trans/cis Resveratrol-D4
- Synonyms
- trans/cis Resveratrol-D4;5-[(E)-2-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)ethenyl]benzene-1,3-diol;Resveratrol D4Q: What is Resveratrol D4 Q: What is the CAS Number of Resveratrol D4 Q: What is the storage condition of Resveratrol D4 Q: What are the applications of Resveratrol D4
- CBNumber
- CB32647480
- Molecular Formula
- C14H8D4O3
- Formula Weight
- 232.267927112
- MOL File
- 1089051-56-8.mol
trans/cis Resveratrol-D4 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: >100 mg/ml,DMSO: >50mg/ml,Ethanol: >50mg/ml,PBS (pH 7.2): <100 μg/ml
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H350May cause cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313IF exposed or concerned: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 13130
- Product name
- trans-Resveratrol-d4
- Purity
- ≥99% deuterated forms (d1-d4)
- Packaging
- 100μg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 13130
- Product name
- trans-Resveratrol-d4
- Purity
- ≥99% deuterated forms (d1-d4)
- Packaging
- 250μg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 13130
- Product name
- trans-Resveratrol-d4
- Purity
- ≥99% deuterated forms (d1-d4)
- Packaging
- 500μg
- Price
- $216
- Updated
- 2024/03/01
- Product number
- 13130
- Product name
- trans-Resveratrol-d4
- Packaging
- 1000μg
- Price
- $380
- Updated
- 2024/03/01
- Product number
- R150001
- Product name
- Resveratrol-d4
- Packaging
- 10mg
- Price
- $475
- Updated
- 2021/12/16
trans/cis Resveratrol-D4 Chemical Properties,Usage,Production
Description
trans-Resveratrol-d4 is intended for use as an internal standard for the quantification of trans-resveratrol by GC- or LC-MS. trans-Resveratrol is a polyphenolic phytoalexin found in a variety of plants, including grapes, that has anti-inflammatory, antioxidant, and anticancer activities. It inhibits the cyclooxygenase and hydroperoxidase activities of COX-1 (EC50s = 15 and 3.7 μM, respectively), but not COX-2 (EC50s = >100 μM and 85 μM, respectively). trans-Resveratrol (3 and 8 mg/kg) inhibits carrageenan-induced paw edema in mice. It inhibits free radical formation in HL-60 human promyelocytic leukemia cells induced by phorbol 12-myristate 13-acetate (TPA; ; EC50 = 27 μM). trans-Resveratrol (1-25 μmol) reduces both the incidence and number of tumors in a two-stage mouse model of skin cancer induced by TPA and 7,12-dimethyl-benz[a]anthracene (DMBA). trans-Resveratrol (200 μM) also activates sirtuin 1 (SIRT1) by 8-fold in vitro and inhibits a variety of targets including ERK1, JNK1, Src, PKCα, aromatase/CYP19, and DNA polymerases α and δ (IC50s = 37, 50, 20, <10, 25, 3.3, and 5 μM, respectively) in vitro and/or ex vivo. It prolongs lifespan in model organisms including C. elegans, D. melanogaster, and mice.
Uses
Resveratrol-d4 is labelled Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression.
trans/cis Resveratrol-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
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