ChemicalBook > CAS DataBase List > 1,7-NAPHTHYRIDIN-8-AMINE

1,7-NAPHTHYRIDIN-8-AMINE

Product Name
1,7-NAPHTHYRIDIN-8-AMINE
CAS No.
17965-82-1
Chemical Name
1,7-NAPHTHYRIDIN-8-AMINE
Synonyms
1,7phthyridin-8-ylamine;1,7-NAPHTHYRIDIN-8-AMINE;8-AMINO-1,7-NAPHTHYRIDINE;8-amino-1,7-naphthypridine;[1,7]Naphthyridin-8-ylaMine;8-Amino-1,7-naphthyridine 95+%;1,7-Naphthyridin-8-amine, 8-Amino-1,7-diazanaphthalene
CBNumber
CB3265183
Molecular Formula
C8H7N3
Formula Weight
145.16
MOL File
17965-82-1.mol
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1,7-NAPHTHYRIDIN-8-AMINE Property

Melting point:
167-170°C
Boiling point:
343.3±27.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
5.54±0.30(Predicted)
form 
solid
color 
Yellow
CAS DataBase Reference
17965-82-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-36-25
Safety Statements 
26-36/37/39-45
Hazard Note 
Irritant
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
N373490
Product name
1,7-Naphthyridin-8-amine
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
N373490
Product name
1,7-Naphthyridin-8-amine
Packaging
250mg
Price
$90
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0006274
Product name
1,7-NAPHTHYRIDIN-8-AMINE
Purity
95.00%
Packaging
5G
Price
$2550
Updated
2021/12/16
Apolloscientific
Product number
OR0830
Product name
8-Amino-1,7-naphthyridine
Purity
95%
Packaging
250mg
Price
$54
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-1-W6
Product name
8-Amino-1,7-naphthyridine
Packaging
250mg
Price
$60
Updated
2021/12/16
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1,7-NAPHTHYRIDIN-8-AMINE Chemical Properties,Usage,Production

Uses

1,7-Naphthyridin-8-amine is a useful chemical in organic synthesis.

Synthesis

452-58-4

56-81-5

17965-82-1

a. A mixture of 2,3-diaminopyridine (5.0 g, 45.9 mmol), glycerol (21.1 g, 229 mmol), sodium 3-nitrobenzenesulfonate (20.6 g, 91.7 mmol), and sulfuric acid (20 mL) was added to water (30 mL), and the reaction was stirred for 16 hours at 135°C. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently slowly poured into an ice-water mixture (150 g). After adjusting the pH of the mixture to neutral with base, it was extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using petroleum ether/ethyl acetate (2:1, v/v) as eluent to afford 1,7-naphthyridin-8-amine as a yellow solid (2.6 g, 39% yield). eSI MS: m/z 146.1 [M + H]+.

References

[1] Patent: US2012/178748, 2012, A1. Location in patent: Page/Page column 47
[2] Patent: WO2017/14323, 2017, A1. Location in patent: Paragraph 0278

1,7-NAPHTHYRIDIN-8-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,7-NAPHTHYRIDIN-8-AMINE Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
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57
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
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Shanghai Sheepchem Co., Ltd.
Tel
+86 (21) 6715-7650
Fax
+86 (21) 6715-7651
Email
sheepchem@163.com
Country
China
ProdList
994
Advantage
60
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
Shanghai Carlow Chemicals Co., Ltd.
Tel
21-33526724 18930996265
Fax
37023730
Email
info@carlowchem.com
Country
China
ProdList
1922
Advantage
58
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View Lastest Price from 1,7-NAPHTHYRIDIN-8-AMINE manufacturers

Career Henan Chemical Co
Product
1,7-NAPHTHYRIDIN-8-AMINE 17965-82-1
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-30