1,7-NAPHTHYRIDIN-8-AMINE
- Product Name
- 1,7-NAPHTHYRIDIN-8-AMINE
- CAS No.
- 17965-82-1
- Chemical Name
- 1,7-NAPHTHYRIDIN-8-AMINE
- Synonyms
- 1,7phthyridin-8-ylamine;1,7-NAPHTHYRIDIN-8-AMINE;8-AMINO-1,7-NAPHTHYRIDINE;8-amino-1,7-naphthypridine;[1,7]Naphthyridin-8-ylaMine;8-Amino-1,7-naphthyridine 95+%;1,7-Naphthyridin-8-amine, 8-Amino-1,7-diazanaphthalene
- CBNumber
- CB3265183
- Molecular Formula
- C8H7N3
- Formula Weight
- 145.16
- MOL File
- 17965-82-1.mol
1,7-NAPHTHYRIDIN-8-AMINE Property
- Melting point:
- 167-170°C
- Boiling point:
- 343.3±27.0 °C(Predicted)
- Density
- 1.292±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 5.54±0.30(Predicted)
- form
- solid
- color
- Yellow
- CAS DataBase Reference
- 17965-82-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-36-25
- Safety Statements
- 26-36/37/39-45
- Hazard Note
- Irritant
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N373490
- Product name
- 1,7-Naphthyridin-8-amine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- N373490
- Product name
- 1,7-Naphthyridin-8-amine
- Packaging
- 250mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CHM0006274
- Product name
- 1,7-NAPHTHYRIDIN-8-AMINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2550
- Updated
- 2021/12/16
- Product number
- OR0830
- Product name
- 8-Amino-1,7-naphthyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $54
- Updated
- 2021/12/16
- Product number
- 3H30-1-W6
- Product name
- 8-Amino-1,7-naphthyridine
- Packaging
- 250mg
- Price
- $60
- Updated
- 2021/12/16
1,7-NAPHTHYRIDIN-8-AMINE Chemical Properties,Usage,Production
Uses
1,7-Naphthyridin-8-amine is a useful chemical in organic synthesis.
Synthesis
452-58-4
56-81-5
17965-82-1
a. A mixture of 2,3-diaminopyridine (5.0 g, 45.9 mmol), glycerol (21.1 g, 229 mmol), sodium 3-nitrobenzenesulfonate (20.6 g, 91.7 mmol), and sulfuric acid (20 mL) was added to water (30 mL), and the reaction was stirred for 16 hours at 135°C. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently slowly poured into an ice-water mixture (150 g). After adjusting the pH of the mixture to neutral with base, it was extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using petroleum ether/ethyl acetate (2:1, v/v) as eluent to afford 1,7-naphthyridin-8-amine as a yellow solid (2.6 g, 39% yield). eSI MS: m/z 146.1 [M + H]+.
References
[1] Patent: US2012/178748, 2012, A1. Location in patent: Page/Page column 47
[2] Patent: WO2017/14323, 2017, A1. Location in patent: Paragraph 0278
1,7-NAPHTHYRIDIN-8-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
1,7-NAPHTHYRIDIN-8-AMINE Suppliers
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- +91-22-26355700
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- India
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- sales@ajchem.in
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- India
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View Lastest Price from 1,7-NAPHTHYRIDIN-8-AMINE manufacturers
- Product
- 1,7-NAPHTHYRIDIN-8-AMINE 17965-82-1
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-30