ChemicalBook > CAS DataBase List > 4'-ethynyl-2-fluoro-2'-deoxyadenosine

4'-ethynyl-2-fluoro-2'-deoxyadenosine

Product Name
4'-ethynyl-2-fluoro-2'-deoxyadenosine
CAS No.
865363-93-5
Chemical Name
4'-ethynyl-2-fluoro-2'-deoxyadenosine
Synonyms
EFdA;E2FDA;Islatravir;Islatravir(MK-8591);MK-8591 (Islatravir);Adenosine Impurity 22;Adenosine Related Compound;2-DEOXY-4-C-ETHYNYL-2-FLUORO-;4'-ethynyl-2-fluoro-2'-deoxyadenosine;2'-Deoxy-4'-ethynyl-2-fluoroadenosine
CBNumber
CB32657140
Molecular Formula
C12H12FN5O3
Formula Weight
293.25
MOL File
865363-93-5.mol
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4'-ethynyl-2-fluoro-2'-deoxyadenosine Property

Melting point:
220.0-221.4 °C (decomp)
Boiling point:
669.2±65.0 °C(Predicted)
Density 
1.72±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:100.0(Max Conc. mg/mL);341.0(Max Conc. mM)
Water:3.57(Max Conc. mg/mL);12.17(Max Conc. mM)
form 
A solid
pka
13.11±0.60(Predicted)
InChI
InChI=1S/C12H12FN5O3/c1-2-12(4-19)6(20)3-7(21-12)18-5-15-8-9(14)16-11(13)17-10(8)18/h1,5-7,19-20H,3-4H2,(H2,14,16,17)/t6-,7+,12+/m0/s1
InChIKey
IKKXOSBHLYMWAE-QRPMWFLTSA-N
SMILES
OC[C@@]1(C#C)O[C@@H](N2C3C(=C(N=C(F)N=3)N)N=C2)C[C@@H]1O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0023675
Product name
Islatravir
Purity
99.94%
Packaging
5mg
Price
$500
Updated
2021/12/16
Axon Medchem
Product number
Axon3191
Product name
Islatravir-EFdA|MK-8591
Purity
99%
Packaging
2x5mg
Price
$792
Updated
2021/12/16
ChemScene
Product number
CS-0023675
Product name
Islatravir
Purity
99.94%
Packaging
10mg
Price
$850
Updated
2021/12/16
ChemScene
Product number
CS-0023675
Product name
Islatravir
Purity
99.94%
Packaging
25mg
Price
$1800
Updated
2021/12/16
ChemScene
Product number
CS-0023675
Product name
Islatravir
Purity
99.94%
Packaging
50mg
Price
$3000
Updated
2021/12/16
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4'-ethynyl-2-fluoro-2'-deoxyadenosine Chemical Properties,Usage,Production

Uses

4'-ethynyl-2-fluoro-2'-deoxyadenosine is a heterocyclic organic compound and can be used as pharmaceutical intermediates.

Uses

MK-?8591 is a carbocyclic nucleoside reverse transcriptase translocation inhibitor and is used as an antiviral with potential use towards the treatment of HIV.

4'-ethynyl-2-fluoro-2'-deoxyadenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4'-ethynyl-2-fluoro-2'-deoxyadenosine manufacturers

Yunbio Tech Co.,Ltd.
Product
4'-ethynyl-2-fluoro-2'-deoxyadenosine EFDA E2FDA 865363-93-5
Price
US $4000.00/g
Min. Order
1g
Purity
95%
Supply Ability
10KGS
Release date
2019-11-28
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4'-ethynyl-2-fluoro-2'-deoxyadenosine/EFDA 865363-93-5
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
10G
Release date
2021-06-18

865363-93-5, 4'-ethynyl-2-fluoro-2'-deoxyadenosineRelated Search:

(R, S)-Adenosyl-L-Methionine ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& Adenosine-5'-diphosphate disodium salt ADENOSINE5'-MONOPHOSPHATESODIUMSALT 8-AMino[1”-(N”-dansyl)-4”-aMinobutyl]-5'-(1-aziridinyl)-5'-deoxy Adenosine Ademetionine 1,4-butanedisulfonate (S, S)-Adenosyl-L-Methionine Ademetionine disulfate tosylate Adenosine 5'-monophosphate Decarboxy-S-adenosylmethionine 5'-DEOXY-5'-METHYLTHIOADENOSINE 2,3,5-TRI-O-ACETYL-6-CHLOROPURINE-9-?-D-RIBOFURANOSIDE S-Adenosyl-L-methionine 2-methylthio-N-6-isopentenyladenosine Adenosine-13C5 2'-O-MB-CAMP SODIUM SALT Adenosine Related Compound 1 Adenosyl Methionine Impurity 2

  • 4'-ethynyl-2-fluoro-2'-deoxyadenosine
  • E2FDA
  • EFdA
  • 2'-deoxy-4'-C-ethynyl-2-fluoro-Adenosine
  • 2'-Deoxy-4'-ethynyl-2-fluoroadenosine
  • 4'-ethynyl-2-fluoro-2'-deoxyadenosine EFDA E2FDA
  • Islatravir
  • Adenosine Related Compound
  • Adenosine Related Compound 6 (MK-8591)
  • (2R,3S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)tetrahydrofuran-3-ol
  • Adenosine, 2'-deoxy-4'-C-ethynyl-2-fluoro-
  • Adenosine Impurity 22
  • 4'-ethynyl-2-fluoro-2'-deoxyadenosine/EFDA
  • Islatravir(MK-8591)
  • (2R,3S,5R)-5-(6-amino-2-fluoro-4H-purin-9(5H)-yl)-2-ethynyl-2-(hydroxymethyl)-tetrahydrofuran-3-ol
  • (2R,3S,5R)-5-(6-amino-2-fluoropurin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol
  • Human immunodeficiency virus,Inhibitor,Islatravir,MK 8591,inhibit,MK8591,Reverse Transcriptase,HIV
  • MK-8591 (Islatravir)
  • 2-DEOXY-4-C-ETHYNYL-2-FLUORO-
  • 865363-93-5
  • C12H12FN5O3