ChemicalBook > CAS DataBase List > EC-17
EC-17
- Product Name
- EC-17
- CAS No.
- 583037-91-6
- Chemical Name
- EC-17
- Synonyms
- EC-17;FTIC-Folate;Folate-FTIC;EC-17 free acid;LMEBZGHLPGBLSU-PMERELPUSA-N;L-Glutamine, N2-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-N-[2-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]ethyl]-
- CBNumber
- CB32658187
- Molecular Formula
- C42H36N10O10S
- Formula Weight
- 872.86
- MOL File
- 583037-91-6.mol
More
Less
EC-17 Property
- Density
- 1.67±0.1 g/cm3(Predicted)
- pka
- 3.57±0.10(Predicted)
More
Less
EC-17 Chemical Properties,Usage,Production
Uses
Folate-FITC (EC-17) is a folic acid derivative that binds to fluorescein isothiocyanate (FITC) to give it fluorescent labeling properties. Folate-fitc is used to induce the formation of pseudo-immunological synapses between anti-FITC CAR T cells and target cells expressing Folate receptors (FRα or FRβ). Folate-FITC can be used to develop controlled CAR-T cell therapies for research in non-small cell lung cancer (NSCLC)[1].
References
[1] Chu W, et al. Bi-specific ligand-controlled chimeric antigen receptor T-cell therapy for non-small cell lung cancer[J]. BioScience trends, 2018, 12(3): 298-308. DOI:10.5582/bst.2018.01048
EC-17 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
EC-17 Suppliers
- Tel
- +1 (866) 930-6790
- Fax
- +1 (866) 333-9607
- info@adooq.com
- Country
- United States
- ProdList
- 2782
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58