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bortezoMib iMpurity H

Product Name
bortezoMib iMpurity H
CAS No.
1446194-56-4
Chemical Name
bortezoMib iMpurity H
Synonyms
Bortezomib Imp.H;Bortezomib impurity H;Bortezomib Impurity S;Linagliptin Impurity CD10120;(S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide;2-Pyrazinecarboxamide, N-[(1S)-2-[(3-methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-;Bortezomib impurity 11/(S)-N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
CBNumber
CB32665558
Molecular Formula
C19H24N4O2
Formula Weight
340.42
MOL File
1446194-56-4.mol
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bortezoMib iMpurity H Property

solubility 
Chloroform (Slightly), Dichloromethane (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C19H24N4O2/c1-14(2)8-9-22-18(24)16(12-15-6-4-3-5-7-15)23-19(25)17-13-20-10-11-21-17/h3-7,10-11,13-14,16H,8-9,12H2,1-2H3,(H,22,24)(H,23,25)/t16-/m0/s1
InChIKey
UJZOAWFAGJVEGQ-INIZCTEOSA-N
SMILES
C1(C(N[C@@H](CC2=CC=CC=C2)C(NCCC(C)C)=O)=O)=NC=CN=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M291300
Product name
N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
Packaging
100mg
Price
$185
Updated
2021/12/16
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bortezoMib iMpurity H Chemical Properties,Usage,Production

Uses

N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is an impurity of Bortezomib (B675700) which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

bortezoMib iMpurity H Preparation Products And Raw materials

Raw materials

Preparation Products

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1446194-56-4, bortezoMib iMpurity HRelated Search:

Bortezomib (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

  • (S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
  • Bortezomib Imp.H
  • Bortezomib Impurity S
  • Bortezomib impurity 11/(S)-N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
  • 2-Pyrazinecarboxamide, N-[(1S)-2-[(3-methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-
  • Bortezomib impurity H
  • Linagliptin Impurity CD10120
  • 1446194-56-4