ChemicalBook > CAS DataBase List > (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

Product Name
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
CAS No.
289472-80-6
Chemical Name
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
Synonyms
Bortezomib IMP;BortezoMib IMpurity;Bortezomib Impuirty 41;Bortezomib Impurity 41;ortezomib Amide Impurity;Bortezomib Amide Impurity;Bortezomib USP Impurity B;Bortezomib Related compaund B;Bortezomib USP Related Compoud B;Bortezomib impurity 6/Bortezomib Amide Impurity
CBNumber
CB62662053
Molecular Formula
C14H14N4O2
Formula Weight
270.29
MOL File
289472-80-6.mol
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(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Property

Melting point:
168-170°C
Boiling point:
619.4±55.0 °C(Predicted)
Density 
1.280±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka
11.92±0.46(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A622540
Product name
N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
Packaging
250mg
Price
$805
Updated
2021/12/16
Alichem
Product number
289472806
Product name
(S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Packaging
1g
Price
$653.12
Updated
2021/12/16
Crysdot
Product number
CD11152975
Product name
(S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Purity
95+%
Packaging
1g
Price
$780
Updated
2021/12/16
Chemenu
Product number
CM276681
Product name
(S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Purity
95%+
Packaging
1g
Price
$1302
Updated
2021/12/16
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(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties,Usage,Production

Uses

N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Suppliers

Canada 1 China 69 India 8 United States 5 Global 83
J & K SCIENTIFIC LTD.
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289472-80-6, (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMideRelated Search:

Bortezomib bortezoMib iMpurity F 2,3-Pyrazinedicarboxylic acid Bortezomib Impurity 35 Bortezomib Impurity 23 tert-Butyl Tosylate DISCONTINUED Bortezomib Impurity 5 1-Chloro-2-methylpropane Bortezomib Impurity 45 BOC-D-Phenylalanine 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide 1-Bromo-2-methylpropane Bortezomib Impurity 47 HCl

  • Bortezomib impurity 6/Bortezomib Amide Impurity
  • Bortezomib Related compaund B
  • 2-PyrazinecarboxaMide, N-[(1S)-2-aMino-2-oxo-1-(phenylMethyl)ethyl]-
  • N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
  • BortezoMib IMpurity
  • Bortezomib Amide Impurity
  • Bortezomib IMP
  • Bortezomib Impurity 41
  • Bortezomib USP Related Compoud B
  • (S)-N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
  • Bortezomib Impuirty 41
  • Bortezomib USP Impurity B
  • N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
  • N-((R)-1-(((S)-3-methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3- phenylpropan-2-yl)pyrazine-2-carboxamide
  • Bortezomib Related Compund B/ Bortezomib Amide Analog
  • N-[(1S)-2-Amino-1-benzyl-2-oxoethyl]pyrazine-2-carboxamide
  • (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaM
  • ortezomib Amide Impurity
  • 289472-80-6