ChemicalBook > CAS DataBase List > (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

Product Name: (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
CAS No.: 289472-80-6
Chemical Name: (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
Synonyms: Bortezomib IMP;BORTEZOMID AMIDE;BortezoMib IMpurity;Bortezomib Impuirty 41;Bortezomib Impurity 41;ortezomib Amide Impurity;Bortezomib Amide Impurity;Bortezomib USP Impurity B;Bortezomib Related compaund B;Bortezomib USP Related Compoud B
CBNumber: CB62662053
Molecular Formula: C14H14N4O2
Formula Weight: 270.29
MOL File: 289472-80-6.mol

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(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Property

Melting point:: 168-170°C
Boiling point:: 619.4±55.0 °C(Predicted)
Density: 1.280±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka: 11.92±0.46(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A622540
Product name: N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
Packaging: 250mg
Price: $805
Updated: 2021/12/16

Alichem

Product number: 289472806
Product name: (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Packaging: 1g
Price: $653.12
Updated: 2021/12/16

Crysdot

Product number: CD11152975
Product name: (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Purity: 95+%
Packaging: 1g
Price: $780
Updated: 2021/12/16

Chemenu

Product number: CM276681
Product name: (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Purity: 95%+
Packaging: 1g
Price: $1302
Updated: 2021/12/16

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(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties,Usage,Production

Uses

N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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289472-80-6, (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMideRelated Search:

Bortezomib bortezoMib iMpurity F 2,3-Pyrazinedicarboxylic acid Bortezomib Impurity 35 Bortezomib Impurity 23 tert-Butyl Tosylate DISCONTINUED Bortezomib Impurity 5 1-Chloro-2-methylpropane Bortezomib Impurity 45 BOC-D-Phenylalanine 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide 1-Bromo-2-methylpropane Bortezomib Impurity 47 HCl

Bortezomib impurity 6/Bortezomib Amide Impurity

Bortezomib Related compaund B

2-PyrazinecarboxaMide, N-[(1S)-2-aMino-2-oxo-1-(phenylMethyl)ethyl]-

N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide

BortezoMib IMpurity

Bortezomib Amide Impurity

Bortezomib IMP

Bortezomib Impurity 41

Bortezomib USP Related Compoud B

(S)-N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Impuirty 41

Bortezomib USP Impurity B

N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide

N-((R)-1-(((S)-3-methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3- phenylpropan-2-yl)pyrazine-2-carboxamide

Bortezomib Related Compund B/ Bortezomib Amide Analog

N-[(1S)-2-Amino-1-benzyl-2-oxoethyl]pyrazine-2-carboxamide

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaM

ortezomib Amide Impurity

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

BORTEZOMID AMIDE

289472-80-6