ChemicalBook > CAS DataBase List > N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- Product Name
- N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- CAS No.
- 289472-81-7
- Chemical Name
- N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- Synonyms
- Bortezomib EP IMP M;Bortezomib USP IMP J;Bortezomib Impurity D;Bortezomib Impurity J;Bortezomib Impurity 48;Bortezomib USP Impurity J;BortezomibHydroxy(1S,2S)-Isomer;Bortezomib USP Related Compoud J;(S)-Hydroxy Des(boric Acid) BortezoMib;(S,S)-Bortezomib Hydroxyisopentyl Amide Analog
- CBNumber
- CB02661665
- Molecular Formula
- C19H24N4O3
- Formula Weight
- 356.42
- MOL File
- 289472-81-7.mol
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N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Property
- Boiling point:
- 672.0±55.0 °C(Predicted)
- Density
- 1.199±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 11.90±0.46(Predicted)
- form
- Solid
- color
- White to Off-White
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N-Bromosuccinimide Price
TRC
- Product number
- H935905
- Product name
- (S)-HydroxyDes(boricAcid)Bortezomib
- Packaging
- 5mg
- Price
- $1455
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CCH0032708
- Product name
- N-((S)-1-(((S)-1-HYDROXY-3-METHYLBUTYL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)PYRAZINE-2-CARBOXAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.22
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CCH0032708
- Product name
- N-((S)-1-(((S)-1-HYDROXY-3-METHYLBUTYL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)PYRAZINE-2-CARBOXAMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1365
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11152974
- Product name
- N-((S)-1-(((S)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
- Purity
- 95+%
- Packaging
- 1g
- Price
- $947
- Updated
- 2021/12/16
Chemenu
- Product number
- CM168043
- Product name
- N-((S)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
- Purity
- 95%+
- Packaging
- 1g
- Price
- $1365
- Updated
- 2021/12/16
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N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties,Usage,Production
Uses
(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Preparation Products And Raw materials
Raw materials
Preparation Products
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289472-81-7, N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMideRelated Search:
2,3-Pyrazinedicarboxylic acid
Bortezomib Impurity 35
Bortezomib Impurity 23
tert-Butyl Tosylate
DISCONTINUED
Bortezomib Impurity 5
1-Chloro-2-methylpropane
Bortezomib Impurity 45
BOC-D-Phenylalanine
bortezoMib iMpurity H
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
Bortezomib Impurity 47 HCl
1-Bromo-2-methylpropane