MK 6096

Product Name: MK 6096
CAS No.: 1088991-73-4
Chemical Name: MK 6096
Synonyms: MK6096;MK-6096;CS-1825;MK 6096;Filorexant;MK 6096;MK6096;MK-6096(Filorexant);Filorexant(MK-6096);filorexant / MK-6096, CID25128145;Inhibitor,inhibit,MK 6096,Orexin Receptor (OX Receptor),MK6096,Filorexant,Hypocretin Receptor,HCRT Receptor
CBNumber: CB32666757
Molecular Formula: C24H25FN4O2
Formula Weight: 420.48
MOL File: 1088991-73-4.mol

More

Less

MK 6096 Property

Boiling point:: 540.2±50.0 °C(Predicted)
Density: 1.203±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 2mg/mL; Ethanol: 5mg/mL
form: A solid
pka: 1.54±0.22(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 29490
Product name: Filorexant
Packaging: 25mg
Price: $421
Updated: 2024/03/01

Cayman Chemical

Product number: 29490
Product name: Filorexant
Packaging: 50mg
Price: $629
Updated: 2024/03/01

Cayman Chemical

Product number: 29490
Product name: Filorexant
Packaging: 5mg
Price: $141
Updated: 2024/03/01

Cayman Chemical

Product number: 29490
Product name: Filorexant
Packaging: 10mg
Price: $253
Updated: 2024/03/01

TRC

Product number: F337008
Product name: Filorexant
Packaging: 5mg
Price: $140
Updated: 2021/12/16

More

Less

MK 6096 Chemical Properties,Usage,Production

Description

Filorexant is a dual antagonist of orexin 1 receptor (OX1R) and OX2R (K_is = 2.5 and 0.31 nM, respectively, for the recombinant human receptors). It selectively inhibits OX1R and OX2R over a panel of more than 170 receptors and enzymes. Filorexant inhibits orexin A-induced calcium mobilization in CHO cells expressing recombinant human OX1R or OX2R (K_b = 11 nM for both). It decreases locomotor activity in rats during the dark cycle when administered at a dose of 10 mg/kg. Filorexant (0.5 mg/kg) reduces the time spent awake and decreases the latency to slow-wave sleep stage 1 (SWS1) and SWS2, but not rapid eye movement (REM) sleep, in dogs. It increases the duration of SWS2, but not SWS1 or REM sleep, in the same model.

Uses

Filorexant is a selective dual orexin receptor antagonist with potent sleep-promoting properties. It has advanced into phase II clinical trials for the treatment of insomnia.

MK 6096 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

MK 6096 Suppliers

CHINA 45 United States 5 Global 50

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

Shanghai Qinghang Chemical Co. Ltd.

Tel: 021-50840321, 18601625411
Fax: 021-50840321
Email: thomasleehz@hotmail.com
Country: China
ProdList: 216
Advantage: 50

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9254
Advantage: 55

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

1088991-73-4, MK 6096Related Search:

Filorexant

MK 6096

MK6096

MK-6096

MK 6096;MK6096

CS-1825

MK-6096(Filorexant)

((2R,5R)-5-(((5-Fluoropyridin-2-yl)oxy)methyl)-2-methylpiperidin-1-yl)(5-methyl-2-(pyrimidin-2-yl)phenyl)methanone MK6096

[(2R,5R)-5-[[(5-Fluoro-2-pyridinyl)oxy]methyl]-2-methyl-1-piperidinyl][5-methyl-2-(2-pyrimidinyl)phenyl]methanone

Filorexant(MK-6096)

[(2R,5R)-5-[(5-FLUOROPYRIDIN-2-YL)OXYMETHYL]-2-METHYLPIPERIDIN-1-YL]-(5-METHYL-2-PYRIMIDIN-2-YLPHENYL)METHANONE

filorexant / MK-6096, CID25128145

Methanone, [(2R,5R)-5-[[(5-fluoro-2-pyridinyl)oxy]methyl]-2-methyl-1-piperidinyl][5-methyl-2-(2-pyrimidinyl)phenyl]-

Inhibitor,inhibit,MK 6096,Orexin Receptor (OX Receptor),MK6096,Filorexant,Hypocretin Receptor,HCRT Receptor

1088991-73-4