Auristatin E

Product Name: Auristatin E
CAS No.: 160800-57-7
Chemical Name: Auristatin E
Synonyms: Auristatin E;Auristatin E,inhibit,ADC Payload,ADC Cytotoxin,Inhibitor,Microtubule/Tubulin;L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-;(2S)-2-[(2S)-2-(dimethylamino)-3-methylbutanamido]-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide;(S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethylbutanamide
CBNumber: CB32667365
Molecular Formula: C40H69N5O7
Formula Weight: 732.01
MOL File: 160800-57-7.mol

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Auristatin E Property

Melting point:: 92-94 °C
Boiling point:: 871.0±65.0 °C(Predicted)
Density: 1.085±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C,unstable in solution, ready to use.
solubility: Soluble in DMSO
form: Solid
pka: 13.66±0.20(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H341Suspected of causing genetic defects

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-3435
Product name: AuristatinE
Purity: 99.36%
Packaging: 1mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-3435
Product name: AuristatinE
Purity: 99.36%
Packaging: 5mg
Price: $440
Updated: 2021/12/16

ChemScene

Product number: CS-3435
Product name: AuristatinE
Purity: 99.36%
Packaging: 10mg
Price: $740
Updated: 2021/12/16

BroadPharm

Product number: BP-23645
Product name: AuristatinE
Purity: 95%
Packaging: 50mg
Price: $1300
Updated: 2021/12/16

DC Chemicals

Product number: DC10138
Product name: AuristatinE
Purity: >98%
Packaging: 100mg
Price: $950
Updated: 2021/12/16

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Auristatin E Chemical Properties,Usage,Production

Description

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent. Auristatin E inhibits tubulin polymerization(1). Auristatin E-antibody cunjugates have proven to be successful anticancer agents.(2)
Ref. 1. Pettit et al. Anticancer Drug Des. 1995 10:529.
Ref. 2. Doronina et al. Nature Biotechnol. 2003 21:778.

Auristatin E Preparation Products And Raw materials

Raw materials

Preparation Products

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Auristatin E Suppliers

China 68 United States 10 Global 78

Shanghai ruichang pharmaceutical technology co., LTD

Tel: 18621054990
Email: maychemicals@sina.com
Country: China
ProdList: 673
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 8084
Advantage: 58

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1874
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 878
Advantage: 55

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4574
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

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View Lastest Price from Auristatin E manufacturers

Hangzhou Huarong Pharm Co., Ltd.

Product: Auristatin E 160800-57-7
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2021-09-15

Zhuozhou Wenxi import and Export Co., Ltd

Product: Auristatin E 160800-57-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Auristatin E 160800-57-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

160800-57-7, Auristatin ERelated Search:

Auristatin F Ozone Feed Mould inhibitor

Auristatin E

L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-

Auristatin E,inhibit,ADC Payload,ADC Cytotoxin,Inhibitor,Microtubule/Tubulin

(S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethylbutanamide

(2S)-2-[(2S)-2-(dimethylamino)-3-methylbutanamido]-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide

160800-57-7

160800-57-8

C40H69N5O7