ChemicalBook > CAS DataBase List > HBX 19818

HBX 19818

Product Name
HBX 19818
CAS No.
1426944-49-1
Chemical Name
HBX 19818
Synonyms
HBX 19818;HBX19818; HBX-19818;HBX 19818, 10 mM in DMSO;HBX 19818,Deubiquitinase,Inhibitor,DUBs,HBX19818,inhibit,HBX-19818;N-[3-[benzyl(methyl)amino]propyl]-9-chloro-5,6,7,8-tetrahydroacridine-2-carboxamide;9-Chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-2-acridinecarboxamide;2-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-
CBNumber
CB32682003
Molecular Formula
C25H28ClN3O
Formula Weight
421.96
MOL File
1426944-49-1.mol
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HBX 19818 Property

Boiling point:
631.2±55.0 °C(Predicted)
Density 
1.206±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:12.5(Max Conc. mg/mL);29.62(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.47(Max Conc. mM)
Water:5.0(Max Conc. mg/mL);0.47(Max Conc. mM)
form 
Solid
pka
13.67±0.20(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-2271
Product name
HBX19818
Purity
98.93%
Packaging
5mg
Price
$160
Updated
2021/12/16
ChemScene
Product number
CS-2271
Product name
HBX19818
Purity
98.93%
Packaging
10mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-2271
Product name
HBX19818
Purity
98.93%
Packaging
50mg
Price
$850
Updated
2021/12/16
ChemScene
Product number
CS-2271
Product name
HBX19818
Purity
98.93%
Packaging
100mg
Price
$1100
Updated
2021/12/16
DC Chemicals
Product number
DC10354
Product name
HBX19818
Purity
>98%
Packaging
100mg
Price
$900
Updated
2021/12/16
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HBX 19818 Chemical Properties,Usage,Production

Uses

HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM.

References

[1] Reverdy C, et al. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. Chem Biol. 2012 Apr 20;19(4):467-77. DOI:10.1016/j.chembiol.2012.02.007

HBX 19818 Preparation Products And Raw materials

Raw materials

Preparation Products

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HBX 19818 Suppliers

ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3506
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7778
Advantage
56
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
12476
Advantage
58

1426944-49-1, HBX 19818Related Search:


  • HBX 19818
  • 9-Chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-2-acridinecarboxamide
  • HBX19818; HBX-19818
  • N-[3-[benzyl(methyl)amino]propyl]-9-chloro-5,6,7,8-tetrahydroacridine-2-carboxamide
  • 2-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-
  • HBX 19818,Deubiquitinase,Inhibitor,DUBs,HBX19818,inhibit,HBX-19818
  • HBX 19818, 10 mM in DMSO
  • 1426944-49-1
  • C25H28ClN3O