ChemicalBook > CAS DataBase List > Afatinib iMpurity

Afatinib iMpurity

Product Name
Afatinib iMpurity
CAS No.
1680184-59-1
Chemical Name
Afatinib iMpurity
Synonyms
Cis-Afatinib;(2Z)-Afatinib;Afatinib (Z)-Isomer;Z-Afatinib? (Afatinib Impurity）;Afatinib Impurity B (2Z)-Afatinib;Afatinib Impurity 18（(2Z) Afatinib）;1-(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-2-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one;2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2Z)-
CBNumber
CB32686692
Molecular Formula
C24H25ClFN5O3
Formula Weight
485.94
MOL File
1680184-59-1.mol
More
Less

Afatinib iMpurity Property

Melting point:
>134°C (dec.)
Boiling point:
676.9±55.0 °C(Predicted)
Density 
1.380±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
11.79±0.43(Predicted)
color 
Pale Yellow to Light Yellow
Stability:
Light Sensitive
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
A355305
Product name
(2Z)-Afatinib
Packaging
0.5mg
Price
$475
Updated
2021/12/16
TRC
Product number
A355305
Product name
(2Z)-Afatinib
Packaging
1mg
Price
$870
Updated
2021/12/16
More
Less

Afatinib iMpurity Chemical Properties,Usage,Production

Uses

(2Z)-Afatinib is a structural analogue of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Afatinib iMpurity Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Afatinib iMpurity Suppliers

China 45 India 4 United States 3 Global 52
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10413
Advantage
58

1680184-59-1, Afatinib iMpurityRelated Search:

Afatinib Impurity 3 Afatinib Impurity 19 Afatinib Impurity 7 Afatinib IMpurity F R-afatinib Afatinib Afatinib Impurity 10 N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine 4-Hydroxy 4-Dedimethylamino Afatinib AfatinibHydrolytic impurity Afatinib Impurity 15 Afatinib Impurity 2 Afatinib Impurity 18 Afatinib Impurity 6 Afatinib IMpurity E Afatinib Impurity 9 Afatinib Impurity 14 Afatinib Impurity 17

  • (2Z)-Afatinib
  • Afatinib (Z)-Isomer
  • Cis-Afatinib
  • 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2Z)-
  • Afatinib Impurity 18（(2Z) Afatinib）
  • 1-(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-2-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
  • Afatinib Impurity B (2Z)-Afatinib
  • Z-Afatinib? (Afatinib Impurity）
  • 1680184-59-1