ChemicalBook > CAS DataBase List > (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid

(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid

Product Name
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid
CAS No.
865231-46-5
Chemical Name
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid
Synonyms
AMG 837;CS-1283;AMG-837; AMG837;(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid;Benzenepropanoic acid, β-1-propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-, (βS)-;(betaS)-beta-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid;(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid (AMG-837 free acid) 1259389-38-2 (calium salt hydrate)
CBNumber
CB32693371
Molecular Formula
C26H21F3O3
Formula Weight
438.44
MOL File
865231-46-5.mol
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(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Property

Melting point:
139-142 °C
Boiling point:
565.8±50.0 °C(Predicted)
Density 
1.251±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
4.20±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21815
Product name
AMG 837
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
21815
Product name
AMG 837
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
21815
Product name
AMG 837
Purity
≥98%
Packaging
10mg
Price
$213
Updated
2024/03/01
Cayman Chemical
Product number
21815
Product name
AMG 837
Purity
≥98%
Packaging
25mg
Price
$485
Updated
2024/03/01
TRC
Product number
A614410
Product name
AMG837
Packaging
50mg
Price
$655
Updated
2021/12/16
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(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Chemical Properties,Usage,Production

Uses

AMG 837 is a potent GPR40 agonist. GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity.

(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid Suppliers

Shanghai Boyle Chemical Co., Ltd.
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86-21-57758967
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China
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MedChemexpress LLC
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021-58955995
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609-228-5909
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United States
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SINO High Goal Chemical Technology Co., Ltd.
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2469917557
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China
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Shanghai Lollane Biological Technology Co.,Ltd.
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SPIRO PHARMA
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Amadis Chemical Company Limited
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Dezhou LonWel Pharmaceutical Technology Co., Ltd.
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China
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Musechem
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View Lastest Price from (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid manufacturers

Zhejiang J&C Biological Technology Co.,Limited
Product
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid 865231-46-5
Price
US $1.00/kh
Min. Order
1kh
Purity
99%
Supply Ability
10
Release date
2022-02-25

865231-46-5, (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acidRelated Search:


  • (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid
  • AMG 837
  • (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid (AMG-837 free acid) 1259389-38-2 (calium salt hydrate)
  • (betaS)-beta-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid
  • AMG-837; AMG837
  • CS-1283
  • Benzenepropanoic acid, β-1-propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-, (βS)-
  • 865231-46-5
  • C26H21F3O3