ChemicalBook > CAS DataBase List > 4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid

4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid

Product Name
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid
CAS No.
402849-27-8
Chemical Name
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid
Synonyms
Indomethacin Impurity F;Indometacin Impurity 14;Indapamide EP Impurity F;Indomethacin EP Impurity F;Indometacin EP Impurity F;Indometacin (Indomethacin) EP Impurity F;Indomethacin (Indometacin) EP Impurity F;Indomethacin Impurity 6(Indomethacin EP Impurity F);Indometacin 1,2-Propylene Glycol Esters (Mixture of Isomers);4-Chloro-N''-(4-chlorobenzoyl)-N-(4-methoxyphenyl)benzohydrazide
CBNumber
CB32695340
Molecular Formula
C21H16Cl2N2O3
Formula Weight
415.27
MOL File
402849-27-8.mol
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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Property

Melting point:
159-163°C
Density 
1.370±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Soncited)
form 
Solid
pka
9.41±0.46(Predicted)
color 
White to Pale Beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C365540
Product name
4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazideBenzoicAcid
Packaging
100mg
Price
$120
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
44423
Product name
4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazideBenzoicAcid
Packaging
250mg
Price
$650
Updated
2021/12/16
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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Chemical Properties,Usage,Production

Uses

4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid is an impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.

4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid Suppliers

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402849-27-8, 4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic AcidRelated Search:

Indometacin Impurity 16 4-Chloro-N-(4-Methoxyphenyl)benzaMide, 97% IndoMethacin DiaMide Indometacin EP Impurity G Benzoic acid, 4-chloro-, 2,3-dihydroxypropyl ester 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-hydroxypropyl ester Indometacin Impurity 15 Indometacin Impurity 18 Methanone, (4-chlorophenyl)[2,6-dichloro-4-(hydroxymethyl)phenyl]- Indometacin Impurity 17 Indometacin EP Impurity D 2-(4-METHOXYPHENYL)HYDRAZINESULFONIC ACID SODIUM SALT MONOHYDRATE 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 4-Chlorobenzoic acid 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester Indometacin methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate Indomethacin-d4

  • Indapamide EP Impurity F
  • Indomethacin EP Impurity F
  • Indometacin Impurity 14
  • Indomethacin Impurity 6(Indomethacin EP Impurity F)
  • Indometacin EP Impurity F
  • Indomethacin Impurity F
  • Indometacin (Indomethacin) EP Impurity F
  • Indomethacin impurity 5/Indomethacin EP Impurity F/2-(4-Chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide-4-chloro-benzoic acid
  • Indomethacin (Indometacin) EP Impurity F
  • 4-Chloro-N''-(4-chlorobenzoyl)-N-(4-methoxyphenyl)benzohydrazide
  • Indometacin 1,2-Propylene Glycol Esters (Mixture of Isomers)
  • Benzoic acid, 4-chloro-, 2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide (Indometacin Impurity)
  • Benzoic acid, 4-chloro-, 2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide
  • 4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
  • 402849-27-8
  • Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals