4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole

Product Name: 4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
CAS No.: 457961-34-1
Chemical Name: 4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
Synonyms: Cy1001;AA92593;AA92593 >=98% (HPLC);1-(4-Methoxy-3-methyl-benzenesulfonyl)-piperidine;1-[(4-Methoxy-3-methylphenyl)sulphonyl]piperidine;Piperidine, 1-[(4-methoxy-3-methylphenyl)sulfonyl]-;Per1,AA-92593,Melanopsin,α-MSH,AA92593,inhibit,Inhibitor,OPN4,AA 92593,Melanoma,CHO;4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole
CBNumber: CB32696509
Molecular Formula: C13H19NO3S
Formula Weight: 269.36
MOL File: 457961-34-1.mol

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4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Property

storage temp.: -20°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36-37-38
Safety Statements: 26
WGK Germany: 3
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0865
Product name: AA92593
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $125
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0865
Product name: AA92593
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $478
Updated: 2024/03/01

Sigma-Aldrich

Product number: 5.09267
Product name: Opn4 Antagonist - CAS 457961-34-1 - Calbiochem
Purity: Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC?? = 665 nM; using CHO transfectants).
Packaging: 10MG
Price: $148
Updated: 2024/03/01

AK Scientific

Product number: SYN5091
Product name: AA92593
Packaging: 100mg
Price: $850
Updated: 2021/12/16

DC Chemicals

Product number: DC43509
Product name: AA92593
Purity: >98%
Packaging: 100mg
Price: $400
Updated: 2021/12/16

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4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Chemical Properties,Usage,Production

Uses

AA92593 has been used as a selective melanopsin inhibitor.

Biochem/physiol Actions

AA92593 is an opsinamide, a potent antagonist of melanopsin-mediated phototransduction with an IC50 of 665 nM in a Ca2+ flux assay in CHO cells expressing melanopsin (Opn4) and selectivity > 10 μM at 74 common biological targets. AA41612 is believed to act by competing for binding to melanopsin. AA41612 inhibited mouse pupillary light reflex and light aversion in vivo. AA92593 and similar compounds might be useful in alleviating the photophobia associated with migraine.

4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole Suppliers

China 33 United Kingdom 2 United States 6 Global 41

Sigma-Aldrich

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457961-34-1, 4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisoleRelated Search:

METHYLERGONOVINE 1-Methylpyrazole Methyl stenbolone

1-[(4-Methoxy-3-methylphenyl)sulphonyl]piperidine

4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole

1-(4-Methoxy-3-methyl-benzenesulfonyl)-piperidine

AA92593

Cy1001

Piperidine, 1-[(4-methoxy-3-methylphenyl)sulfonyl]-

AA92593 >=98% (HPLC)

Per1,AA-92593,Melanopsin,α-MSH,AA92593,inhibit,Inhibitor,OPN4,AA 92593,Melanoma,CHO

457961-34-1