ChemicalBook > CAS DataBase List > (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione

(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione

Product Name
(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
CAS No.
1486466-31-2
Chemical Name
(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
Synonyms
Clobetasol EP Impurity J;Clobetasol impurity J (PhEur);Clobetasol Propionate EP IMP J;Clobetasol Propionate Impurity J;Clobetasol Propionate EP Impurity J;Clobetasol Related Compound A (USP);Clobetasol Propionate Impurity J(EP);CLOBETASOL PROPIOTE RELATED COMPOUND A;Clobetasol Propionate 17α-spiro Compound;Clobetasol Propionate USP Related Compound A
CBNumber
CB32709289
Molecular Formula
C25H30ClFO4
Formula Weight
448.95
MOL File
1486466-31-2.mol
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(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Property

Melting point:
>276°C (dec.)
Boiling point:
563.7±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Dioxane (Very Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
pka
12.96±0.70(Predicted)
color 
White to off-White
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Safety

Hazard Codes 
T
Risk Statements 
61-48/20/21-53-62
Safety Statements 
53-36/37-45
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
F591800
Product name
9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
Packaging
5mg
Price
$65
Updated
2021/12/16
TRC
Product number
F591800
Product name
9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
Packaging
50mg
Price
$180
Updated
2021/12/16
TRC
Product number
F591800
Product name
9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
Packaging
250mg
Price
$785
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
68641
Product name
(17R)-4??-Chloro-5??-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2??(3??H)-furan]-3,3??-dione
Packaging
50mg
Price
$650
Updated
2021/12/16
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(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Chemical Properties,Usage,Production

Uses

(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione, is an impurity of Clobetasol (C583490), a topical corticosteroid, and a Glucocorticoid, used as an anti-inflammatory agent.

(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Suppliers

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1486466-31-2, (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dioneRelated Search:

Clobetasol 21-Chloro-9-fluoro-11β,17-dihydroxy-16α-Methylpregna-1,4-diene-3,20-dione 17-Propionate 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate BETAMETHASONE 21-PROPIONATE (11β)-21-Chloro-9-fluoro-11-hydroxy-16-Methylpregna-1,4,16-triene-3,20-dione 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate 9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate 9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate

  • 9α-Fluoro-11β-hydroxy-16-β-Methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one
  • Clobetasol impurity J (PhEur)
  • Clobetasol Related Compound A (USP)
  • Clobetasol Propionate EP Impurity J
  • Clobetasol Propionate Impurity 10(Clobetasol Propionate EP Impurity J)
  • 2-tert-butyl-1'-(7-methyl-3a,7a-dihydro-1H-indazole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
  • Clobetasol Propionate USP Related Compound A/(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione
  • Clobetasol Propionate USP Related Compound A
  • Clobetasol Propionate EP IMP J
  • Clobetasol Propionate Impurity J(EP)
  • Clobetasol EP Impurity J
  • (17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione
  • Clobetasol Propionate Impurity J
  • Clobetasol Propionate EP Impurity J/ Clobetasol Propionate Related Compound A
  • Clobetasol impurity J (Y0000571)Q: What is Clobetasol impurity J (Y0000571) Q: What is the CAS Number of Clobetasol impurity J (Y0000571)
  • Clobetasol Propionate 17α-spiro Compound
  • 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one
  • (17R)-4′-chloro-5′-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2′(3′h)-furan]-3,3′-dione(17α-spirocompound)
  • (11β,16β)-22-Chloro-17,23-epoxy-9-fluoro-1-hydroxy-16-methyl-21,26,27-trinorcholesta-1,4,22-triene-3,20-dione
  • Clobetasol Propionate EP Impurity J (Clobetasol Propionate USP Related Compound A)
  • CLOBETASOL PROPIOTE RELATED COMPOUND A
  • 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrostα-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
  • (17R)-4'-Chloro-5'-ethyl-9-fluoro-11beta-hydroxy-16beta-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
  • 17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
  • (17R)-4'-Chloro-5'-ethyl-9-fluoro-11beta-hydroxy-16beta-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
  • 2-tert-butyl-1'-(7-methyl-3a,7a-dihydro-1H-indazole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
  • 1486466-31-2
  • C25H30ClFO4