ChemicalBook > CAS DataBase List > 4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide

4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide

Product Name
4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide
CAS No.
835621-11-9
Chemical Name
4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide
Synonyms
BAY 75-7495;nib N-oxyde M2;RegoraféRegorafenib N-Oxide;Regorafenib impurity M;REGORAFéNIB N-OXYDE M2;Regorafenib N-Oxide(M2);Regorafenib impurity 06;Regorafénib N-oxyde (M2);Regorafenib Impurities66
CBNumber
CB32716054
Molecular Formula
C21H15ClF4N4O4
Formula Weight
498.81
MOL File
835621-11-9.mol
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4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide Property

Boiling point:
580.5±50.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: soluble
form 
A solid
pka
12.07±0.70(Predicted)
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
R143315
Product name
Regorafenib(Pyridine)-N-oxide
Packaging
100mg
Price
$1390
Updated
2021/12/16
ChemScene
Product number
CS-M2818
Product name
RegorafénibN-oxydeM2
Purity
99.54%
Packaging
5mg
Price
$110
Updated
2021/12/16
ChemScene
Product number
CS-M2818
Product name
RegorafénibN-oxydeM2
Purity
99.54%
Packaging
10mg
Price
$180
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
48555
Product name
Regorafenib(Pyridine)-N-oxide
Packaging
10mg
Price
$390
Updated
2021/12/16
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4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide Chemical Properties,Usage,Production

Uses

Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.

4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide Suppliers

Canada 1 China 57 India 3 United States 7 Global 68
Artis Chemistry (Shanghai) Co. Ltd.
Tel
86-21-60936353
Fax
86-21-60936352
Country
China
ProdList
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Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-52878169 15701683040
Email
sales@bjcomparison.com
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China
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4693
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ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
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Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
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1511893459@qq.com
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China
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SPIRO PHARMA
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Fax
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eric_feng1954@126.com
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China
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Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2862
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Clearsynth Canada Inc.
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+1.415.685.4395
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+1.415.685.4395
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enquiry@clearsynth.com
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Canada
ProdList
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Roark Standards
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0755-83552066 15986688328
Fax
0755-83552066
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service@roarkstandards.com
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China
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Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
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Country
China
ProdList
131981
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58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
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835621-11-9, 4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxideRelated Search:

Regorafenib Impurity 5 Regorafenib Impurity 9 Regorafenib Impurity 4 Regorafenib Impurity 16 2-[2-(2-Methyl-5-nitroiMidazol-1-yl)ethoxy]ethanol 5-Nitro-1H-iMidazole-1-ethanol Regorafenib impurity D Regorafenib N-Oxide N-Glucuronide Regorafenib Impurity 7 Regorafenib Impurity 8 Regorafenib Impurity 3 Regorafenib Impurity 25 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE N-Desmethyl Regorafenib N-Oxide (M5 Metabolite) N-Desmethyl Regorafenib Regorafenib Impurity 6 INDEX NAME NOT YET ASSIGNED 4-(4-amino-3-(4-amino-3-(4-amino-3-fluorophenoxy)phenoxy)phenoxy)-N-methylpicolinamide

  • 4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide
  • Regorafenib N-Oxide (M2 Metabolite)
  • Regorafenib N-Oxide(M2)
  • Regorafenib N-Oxide
  • Regorafenib impurity M
  • Regorafenib Pyridine-N-Oxide
  • Regorafénib N-oxyde (M2)
  • 2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, 1-oxide
  • 4-(4-(3-(4-chloro-3-(trifluoromethyl)
  • BAY 75-7495
  • Regorafenib impurity 5/ Regorafenib (Pyridine)-N-oxide/4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 1-Oxide
  • REGORAFéNIB N-OXYDE M2
  • nib N-oxyde M2
  • Regoraf&eacute
  • Regorafenib metabolite M2 (N-oxide)
  • Regorafenib metabolite M2
  • Regorafenib Impurities66
  • Azilsartan medoxomil impurity259
  • Regorafenib Impurities07
  • Regorafenib 13CD3 N-OxideQ: What is Regorafenib 13CD3 N-Oxide Q: What is the CAS Number of Regorafenib 13CD3 N-Oxide Q: What is the storage condition of Regorafenib 13CD3 N-Oxide Q: What are the applications of Regorafenib 13CD3 N-Oxide
  • Regorafenib N-oxide (M2 Metabolite)Q: What is Regorafenib N-oxide (M2 Metabolite) Q: What is the CAS Number of Regorafenib N-oxide (M2 Metabolite) Q: What is the storage condition of Regorafenib N-oxide (M2 Metabolite) Q: What are the applications of Regorafenib N-oxide (M2 Metabolite)
  • Inhibitor,Regorafénib N oxyde (M2),Regorafénib Noxyde (M2),Regorafénib N-oxyde (M2),inhibit,Regorafénib N-oxyde (M-2),Platelet-derived growth factor receptor,PDGFR,Drug Metabolite
  • Regorafenib impurity 06
  • 835621-11-9