4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

Product Name: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
CAS No.: 757251-39-1
Chemical Name: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
Synonyms: RG-M2;Regofenib impurity 4;Regorafenib USP RC A;Regorafenib Impurity 35;Regorafenib Intermediate;Regorafenib EP Impurity A;4-(4-amino-3-fluorophenoxy);AFP-Picolin Methylamide Impurity;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
CBNumber: CB51486673
Molecular Formula: C13H12FN3O2
Formula Weight: 261.25
MOL File: 757251-39-1.mol

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4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Property

Melting point:: 143 °C
Boiling point:: 459.8±45.0 °C(Predicted)
Density: 1.305
vapor pressure: 0Pa at 20℃
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
form: Solid
pka: 13.92±0.46(Predicted)
color: Orange to Dark Red to Brown
Water Solubility: 190mg/L at 20℃
LogP: 1.3 at 25℃

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Safety

HS Code: 2933.39.9200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0002093
Product name: Regorafenib impurity A
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: Y0002093
Price: $150
Updated: 2024/03/01

TCI Chemical

Product number: A2979
Product name: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide
Purity: >98.0%(HPLC)
Packaging: 200mg
Price: $37
Updated: 2024/03/01

TCI Chemical

Product number: A2979
Product name: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $110
Updated: 2024/03/01

TRC

Product number: A609725
Product name: 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
Packaging: 1g
Price: $315
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0352095
Product name: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $502.98
Updated: 2021/12/16

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4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Chemical Properties,Usage,Production

Chemical Properties

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide has the appearance of a white to yellow powder or crystals, which is stable and non-reactive under normal conditions of use, storage and transport.

Uses

4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.

Definition

ChEBI: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide is an aromatic ether.

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Suppliers

Americas 1 China 220 Europe 1 India 13 Japan 1 Switzerland 1 United Kingdom 1 United States 12 Global 250

Yangzhou juhechang Technology Co., Ltd

Tel: 0514-0514-83662002 13073488988
Fax: 0514-83662002
Email: 13073488988@163.com
Country: China
ProdList: 36
Advantage: 58

Yangzhou QinYuan Pharmaceutical Co., Ltd.

Tel: 0514-80939770 13773367191
Fax: 0514-82664689
Email: yzqyyykj@163.com
Country: China
ProdList: 228
Advantage: 55

Wuhan Yihe Technology Co., Ltd

Tel: 18427358861 18427358864
Email: yihekeji@chembuying.com
Country: China
ProdList: 776
Advantage: 58

Hubei Lidu New Material Technology Co., Ltd

Tel: 19307245857 19307245857
Email: 1763632904@qq.com
Country: China
ProdList: 476
Advantage: 58

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

Wuhan Sunrise Technology Development Co., Ltd.

Tel: 027-027-83314682 13554138826
Fax: +86 (27) 8331-4682
Email: whsrtech@vip.163.com
Country: China
ProdList: 298
Advantage: 62

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4992
Advantage: 50

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View Lastest Price from 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE manufacturers

LY Global chemicals co.,ltd .

Product: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE 757251-39-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98.0%min
Supply Ability: 100kg
Release date: 2023-03-11

Shanghai Rlavie Technology Co ltd

Product: 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 757251-39-1
Price: US $0.00-0.00/G
Min. Order: 1G
Purity: 98%min
Supply Ability: 50kgs/month
Release date: 2022-09-11

Career Henan Chemical Co

Product: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE 757251-39-1
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-13

757251-39-1, 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDERelated Search:

1,3-Benzenediol, 5-fluoro-4-nitro- 4-(4-Fluorophenyl)-1-Methyl- Paroxetine Selexipag Impurity 6 (4-BENZYLOXYCARBONYLAMINOPHENYL)BORONIC ACID, PINACOL ESTER PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE) S-Silodosin 6,6'-bis(2-methyl-2H-tetrazol-5-yl)-3,3'-bipyridine 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid Cabozantinib Impurity E 4-Amino-3-fluorophenol 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrate 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine Regorafenib Regorafenib iMpurity Benzene, 1-chloro-3-isocyanato-5-(trifluoromethyl)- 2-Pyridinecarboxylic acid, 4,5,6-trichloro-, methyl ester 1,3-Benzenediol, 4-amino-5-fluoro-

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-

4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamine

4-(4-amino-3-fluorophenoxy)

4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamid

Regorafenib Impurity 35

4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide

4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYL-2-PYRIDINECARBOXAMIDE

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide EINECS

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE

Regorafenib Intermediate

Regofenib impurity 4

AFP-Picolin Methylamide Impurity

Regorafenib USP RC A

Regorafenib EP Impurity A

AFP-Picolin Methylamide ImpurityQ: What is AFP-Picolin Methylamide Impurity Q: What is the CAS Number of AFP-Picolin Methylamide Impurity Q: What is the storage condition of AFP-Picolin Methylamide Impurity Q: What are the applications of AFP-Picolin Methylamide Impurity

RG-M2

Regorafenib EP Impurity A (Regorafenib USP Related Compound A)

4- (4-Amino-3-fluorophenoxy) - N-methyl-2-pyridylformamide

757251-39-1

797251-39-1

Regorafenib