Ripasudil Hydrochloride

Product Name: Ripasudil Hydrochloride
CAS No.: 223644-02-8
Chemical Name: Ripasudil Hydrochloride
Synonyms: Glanatec;Ripasudil Hydrochloride;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride
CBNumber: CB32738175
Molecular Formula: C15H19ClFN3O2S
Formula Weight: 359.8466632
MOL File: 223644-02-8.mol

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Ripasudil Hydrochloride Property

Melting point:: 258-259 °C (decomp)
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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Ripasudil Hydrochloride Chemical Properties,Usage,Production

Uses

Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.

Uses

Ripasudil Hydrochloride Dihydrate is a derivative of fasudil and a rho kinase inhibitor (1,2). It is used for the treatment of glaucoma and ocular hypertension.

Ripasudil Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Ripasudil Hydrochloride Suppliers

China 6 Global 6

Suzhou Haiheng Biological Pharmaceutical Co., Ltd.

Tel: 0512-65045967 15365387483
Fax: 15365387483
Email: sales@haihengpharm.com
Country: China
ProdList: 94
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19105
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7955
Advantage: 58

Changzhou Bojia Biomedical Technology Co., Ltd.

Tel: 2122619822
Email: czbjpharma@126.com
Country: China
ProdList: 18488
Advantage: 58

Henan Tianfu Chemical Co.,Ltd.

Tel: +86-0371-55170693 +86-19937530512
Fax: 0371-55170693
Email: info@tianfuchem.com
Country: China
ProdList: 21689
Advantage: 55

223644-02-8, Ripasudil HydrochlorideRelated Search:

Ripasudil Ripasudil hydrochloride dihydrate

Ripasudil Hydrochloride

(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride

Glanatec

223644-02-8

C15H18FN3O2SHCl