Ripasudil

Product Name: Ripasudil
CAS No.: 223645-67-8
Chemical Name: Ripasudil
Synonyms: CS-1564;Ripasudil;k115 free base;K-115, Ripasudil;RIPASUDIL HYDROCHLOIDE;RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE;(S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline;4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline;Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-
CBNumber: CB92722374
Molecular Formula: C15H18FN3O2S
Formula Weight: 323.39
MOL File: 223645-67-8.mol

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Ripasudil Property

Boiling point:: 497.2±55.0 °C(Predicted)
Density: 1.293±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Soluble in DMSO
pka: 9.70±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

CSNpharm

Product number: CSN16953
Product name: K-115
Packaging: 5mg
Price: $154
Updated: 2021/12/16

Crysdot

Product number: CD31002611
Product name: K-115freebase
Purity: 98+%
Packaging: 250mg
Price: $515
Updated: 2021/12/16

CSNpharm

Product number: CSN16953
Product name: K-115
Packaging: 25mg
Price: $557
Updated: 2021/12/16

Chemenu

Product number: CM146182
Product name: (S)-4-fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline
Purity: 98%
Packaging: 100mg
Price: $880
Updated: 2021/12/16

Crysdot

Product number: CD31002611
Product name: K-115freebase
Purity: 98+%
Packaging: 1g
Price: $1290
Updated: 2021/12/16

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Ripasudil Chemical Properties,Usage,Production

Description

Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.

Definition

ChEBI: Ripasudil is a member of isoquinolines.

Ripasudil Preparation Products And Raw materials

Raw materials

Preparation Products

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Ripasudil Suppliers

China 43 India 3 United Kingdom 2 United States 6 Global 54

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chemvon Biotechnology Co., Ltd

Tel: 021-50790412
Fax: +86-21-50790419
Email: info@chemvon.com
Country: China
ProdList: 371
Advantage: 57

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

Suzhou Haiheng Biological Pharmaceutical Co., Ltd.

Tel: 0512-65045967 15365387483
Fax: 15365387483
Email: sales@haihengpharm.com
Country: China
ProdList: 94
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8012
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

223645-67-8, RipasudilRelated Search:

Ripasudil hydrochloride dihydrate Ripasudil Hydrochloride CAL-101 Temsirolimus Rapamycin Icotinib Radotinib FASUDIL

k115 free base

Ripasudil

4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline

RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE

CS-1564

K-115, Ripasudil

Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-

RIPASUDIL HYDROCHLOIDE

(S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline

223645-67-8