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Ripasudil Hydrochloride

Product Name
Ripasudil Hydrochloride
CAS No.
223644-02-8
Chemical Name
Ripasudil Hydrochloride
Synonyms
Glanatec;Ripasudil Hydrochloride;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride
CBNumber
CB32738175
Molecular Formula
C15H19ClFN3O2S
Formula Weight
359.8466632
MOL File
223644-02-8.mol
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Ripasudil Hydrochloride Property

Melting point:
258-259 °C (decomp)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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Ripasudil Hydrochloride Chemical Properties,Usage,Production

Uses

Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.

Uses

Ripasudil Hydrochloride Dihydrate is a derivative of fasudil and a rho kinase inhibitor (1,2). It is used for the treatment of glaucoma and ocular hypertension.

Ripasudil Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Ripasudil Hydrochloride Suppliers

Suzhou Haiheng Biological Pharmaceutical Co., Ltd.
Tel
0512-65045967 15365387483
Fax
15365387483
Email
sales@haihengpharm.com
Country
China
ProdList
94
Advantage
55
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Wuhan Topule
Tel
+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
8084
Advantage
58
Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
Email
czbjpharma@126.com
Country
China
ProdList
18478
Advantage
58
Henan Tianfu Chemical Co.,Ltd.
Tel
+86-0371-55170693 +86-19937530512
Fax
0371-55170693
Email
info@tianfuchem.com
Country
China
ProdList
21634
Advantage
55

223644-02-8, Ripasudil HydrochlorideRelated Search:


  • Ripasudil Hydrochloride
  • (2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride
  • Glanatec
  • 223644-02-8
  • C15H18FN3O2SHCl