ChemicalBook > CAS DataBase List > Ripasudil Hydrochloride
Ripasudil Hydrochloride
- Product Name
- Ripasudil Hydrochloride
- CAS No.
- 223644-02-8
- Chemical Name
- Ripasudil Hydrochloride
- Synonyms
- Glanatec;Ripasudil Hydrochloride;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride
- CBNumber
- CB32738175
- Molecular Formula
- C15H19ClFN3O2S
- Formula Weight
- 359.8466632
- MOL File
- 223644-02-8.mol
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Ripasudil Hydrochloride Property
- Melting point:
- 258-259 °C (decomp)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
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Ripasudil Hydrochloride Chemical Properties,Usage,Production
Uses
Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.
Uses
Ripasudil Hydrochloride Dihydrate is a derivative of fasudil and a rho kinase inhibitor (1,2). It is used for the treatment of glaucoma and ocular hypertension.
Ripasudil Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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Ripasudil Hydrochloride Suppliers
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- 0512-65045967 15365387483
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- 15365387483
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- China
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- meitaochem@126.com
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- czbjpharma@126.com
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- China
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- +86-0371-55170693 +86-19937530512
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- 0371-55170693
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