N-(1-PYRENYL)MALEIMIDE Property

Melting point:

235-237 °C(lit.)

Boiling point:

438.82°C (rough estimate)

Density 

1.2310 (rough estimate)

refractive index 

1.5180 (estimate)

storage temp. 

Refrigerator

solubility 

Soluble in chloroform, N,Ndimethylformamide, dimethyl sulfoxide, ethanol, methanol

form 

Solid

pka

–1.21±0.20, most basic, temperature: 25°C

color 

Yellow needles;Gold needles

λmax

338nm, 325nm (MeOH)

BRN 

1542661

Major Application

Dendrimers; dye functionalized single-wall carbon nanotube (SWNT) conjugated polymer devices; photovoltaic cells; polymer-coated gold electrodes; fluorescent polymers; radio-fluorogenic gel; in sequencecontrolled polymerizations; rubber

Biological Applications

Analyzing molecular aspects of muscle contraction; detecting nucleic acids, proteins; determining/evaluating cell activity; diagnosing/treating Parkinson’s disease; monitoring/studying ribosomal structure and conformation; studying nicotinic acetylcholine receptor (AChR) structure; sulfhydryl reagent

CAS DataBase Reference

42189-56-0(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

1

F 

8-10-21

HS Code 

29251900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

N-(1-PYRENYL)MALEIMIDE Chemical Properties,Usage,Production

Chemical Properties

N-(1-PYRENYL)MALEIMIDE is Yellow Solid

Uses

N-(1-PYRENYL)MALEIMIDE is a fluorescent sulfhydryl reagent that can form excited-state dimers which emit at longer wavelenghts than the lone excited fluorophore.

Uses

Reactant used in synthesis of: • ;Oligodeoxynucleotide derivatives1 • ;Polymer conjugates of immunogenic peptides2 • ;Modified oligonucleotides for biosensing applications3,Reactant: • ;Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers4• ;Used as derivitizing agent for determination of glutathione disulfide levels in biological samples5