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Maleimide

Product Name
Maleimide
CAS No.
541-59-3
Chemical Name
Maleimide
Synonyms
1h-pyrrole-2,5-dione;Maleic imide;PYRROLE-2,5-DIONE;Maleinimide;MALEIC ACID IMIDE;MaleiMide, 98% 10GR;NSC 13684;MALEIMIDE;maleicimide;Maleimide>
CBNumber
CB6358686
Molecular Formula
C4H3NO2
Formula Weight
97.07
MOL File
541-59-3.mol
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Maleimide Property

Melting point:
91-93 °C (lit.)
Boiling point:
97-103°C 5mm
Density 
1,2493 g/cm3
refractive index 
1.4543 (estimate)
Flash point:
97-103°C/5mm
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
pka
8.52±0.20(Predicted)
form 
Fine Crystalline Powder
color 
White to slightly yellow
Water Solubility 
SOLUBLE
λmax
280nm(EtOH)(lit.)
BRN 
106910
InChIKey
PEEHTFAAVSWFBL-UHFFFAOYSA-N
CAS DataBase Reference
541-59-3(CAS DataBase Reference)
NIST Chemistry Reference
1H-pyrrole-2,5-dione(541-59-3)
EPA Substance Registry System
1H-Pyrrole-2,5-dione (541-59-3)
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Safety

Hazard Codes 
T,C
Risk Statements 
25-34-43-36/37/38-36
Safety Statements 
26-36/37/39-45-37/39-28A-7/9
RIDADR 
UN 2923 8/PG 2
WGK Germany 
3
RTECS 
ON4800000
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29251995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129585
Product name
Maleimide
Purity
99%
Packaging
2g
Price
$40.4
Updated
2024/03/01
Sigma-Aldrich
Product number
129585
Product name
Maleimide
Purity
99%
Packaging
10g
Price
$118
Updated
2024/03/01
TCI Chemical
Product number
M0018
Product name
Maleimide
Purity
>98.0%(T)
Packaging
5g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
M0018
Product name
Maleimide
Purity
>98.0%(T)
Packaging
25g
Price
$190
Updated
2024/03/01
Alfa Aesar
Product number
A13135
Product name
Maleimide, 98+%
Packaging
5g
Price
$58.8
Updated
2024/03/01
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Maleimide Chemical Properties,Usage,Production

Chemical Properties

slight yellow crystalline powder

Uses

Reacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry.

Uses

Rhodium-catalyzed conjugate arylation with arylboronic acids.1

Definition

ChEBI: A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure.

General Description

Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.

Hazard

A poison.

Safety Profile

Poison by intraperitoneal and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify it by sublimation in a vacuum. The UV has max at 216 and 280nm in EtOH. [de Wolf & van de Straete Bull Soc Chim Belg 44 288 1935, UV: Rondestvedt et al. J Am Chem Soc 78 6115 1956, IR: Chiorboli & Mirone Ann Chim (Rome) 42 681 1952, Beilstein 21/10 V 3.]

Maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

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Maleimide Suppliers

Qingdao Ruifengyuan Chemical Co., Ltd.
Tel
13375559818 13375559818
Email
cfy69@163.com
Country
China
ProdList
226
Advantage
58
Shanghai RC Chemicals Co., Ltd.
Tel
21-58661250 18217085189
Fax
+86-21-58661251
Email
3059772675@qq.com
Country
China
ProdList
99
Advantage
64
Jinan Aery Pharmaceutical Co,.Ltd
Tel
0531-81263406
Fax
86-0531-58591634
Email
sales@aerpharm.com
Country
China
ProdList
21
Advantage
55
Zheda Panaco Chemical Engineering Co., Ltd
Tel
0571-86770761
Fax
+0571-87984136
Email
zhedapanaco02@zhedachem.com
Country
China
ProdList
100
Advantage
60
Beijing Leaderherb Bio-Tech. Co., LTD.
Tel
010-51288246
Email
300abc@sina.com
Country
China
ProdList
59
Advantage
58
Hangzhou Yijing Technology Co., Ltd
Tel
15068777134
Email
1289372011@qq.com
Country
China
ProdList
1611
Advantage
58
SHANDONG XINGRUNDA CHEMICAL CO.,LTD
Tel
18615348689 18615348689
Email
hclt1978@163.com
Country
China
ProdList
11
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
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View Lastest Price from Maleimide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Maleimide 541-59-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.0%
Supply Ability
1kg/month
Release date
2023-02-13
Hebei Mojin Biotechnology Co., Ltd
Product
Maleimide 541-59-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-06
Hebei Guanlang Biotechnology Co,.LTD
Product
Maleimide 541-59-3
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2022-01-25

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