Maleimide

ChemicalBook > CAS DataBase List > Maleimide

Product Name: Maleimide
CAS No.: 541-59-3
Chemical Name: Maleimide
Synonyms: 1h-pyrrole-2,5-dione;Maleic imide;PYRROLE-2,5-DIONE;Maleinimide;MALEIC ACID IMIDE;MaleiMide, 98% 10GR;NSC 13684;MALEIMIDE;maleicimide;Maleimide>
CBNumber: CB6358686
Molecular Formula: C4H3NO2
Formula Weight: 97.07
MOL File: 541-59-3.mol

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Maleimide Property

Melting point:: 91-93 °C (lit.)
Boiling point:: 97-103°C 5mm
Density: 1,2493 g/cm³
refractive index: 1.4543 (estimate)
Flash point:: 97-103°C/5mm
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
pka: 8.52±0.20(Predicted)
form: Fine Crystalline Powder
color: White to slightly yellow
Water Solubility: SOLUBLE
λmax: 280nm(EtOH)(lit.)
BRN: 106910
InChIKey: PEEHTFAAVSWFBL-UHFFFAOYSA-N
CAS DataBase Reference: 541-59-3(CAS DataBase Reference)
NIST Chemistry Reference: 1H-pyrrole-2,5-dione(541-59-3)
EPA Substance Registry System: 1H-Pyrrole-2,5-dione (541-59-3)

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Safety

Hazard Codes: T,C
Risk Statements: 25-34-43-36/37/38-36
Safety Statements: 26-36/37/39-45-37/39-28A-7/9
RIDADR: UN 2923 8/PG 2
WGK Germany: 3
RTECS: ON4800000
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29251995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 129585
Product name: Maleimide
Purity: 99%
Packaging: 2g
Price: $40.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 129585
Product name: Maleimide
Purity: 99%
Packaging: 10g
Price: $118
Updated: 2024/03/01

TCI Chemical

Product number: M0018
Product name: Maleimide
Purity: >98.0%(T)
Packaging: 5g
Price: $54
Updated: 2024/03/01

TCI Chemical

Product number: M0018
Product name: Maleimide
Purity: >98.0%(T)
Packaging: 25g
Price: $190
Updated: 2024/03/01

Alfa Aesar

Product number: A13135
Product name: Maleimide, 98+%
Packaging: 5g
Price: $58.8
Updated: 2024/03/01

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Maleimide Chemical Properties,Usage,Production

Chemical Properties

slight yellow crystalline powder

Uses

Reacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry.

Uses

Rhodium-catalyzed conjugate arylation with arylboronic acids.1

Definition

ChEBI: A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure.

General Description

Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.

Hazard

A poison.

Safety Profile

Poison by intraperitoneal and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify it by sublimation in a vacuum. The UV has max at 216 and 280nm in EtOH. [de Wolf & van de Straete Bull Soc Chim Belg 44 288 1935, UV: Rondestvedt et al. J Am Chem Soc 78 6115 1956, IR: Chiorboli & Mirone Ann Chim (Rome) 42 681 1952, Beilstein 21/10 V 3.]

Maleimide Preparation Products And Raw materials

Raw materials

Potassium dichromate Fiber Glass Wool

Preparation Products

N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA 4-MALEIMIDOBUTYRIC ACID N-METHOXYCARBONYLMALEIMIDE

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View Lastest Price from Maleimide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Maleimide 541-59-3
Price: US $120.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-10

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Maleimide 541-59-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98.0%
Supply Ability: 1kg/month
Release date: 2023-02-13

Hebei Weibang Biotechnology Co., Ltd

Product: Maleimide 541-59-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-25

541-59-3, MaleimideRelated Search:

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541-59-3

41-59-3

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