ChemicalBook > CAS DataBase List > Maleimide

Maleimide

Product Name
Maleimide
CAS No.
541-59-3
Chemical Name
Maleimide
Synonyms
1h-pyrrole-2,5-dione;Maleic imide;PYRROLE-2,5-DIONE;Maleinimide;MALEIC ACID IMIDE;MaleiMide, 98% 10GR;NSC 13684;MALEIMIDE;maleicimide;Maleimide>
CBNumber
CB6358686
Molecular Formula
C4H3NO2
Formula Weight
97.07
MOL File
541-59-3.mol
More
Less

Maleimide Property

Melting point:
91-93 °C (lit.)
Boiling point:
97-103°C 5mm
Density 
1,2493 g/cm3
refractive index 
1.4543 (estimate)
Flash point:
97-103°C/5mm
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
pka
8.52±0.20(Predicted)
form 
Fine Crystalline Powder
color 
White to slightly yellow
Water Solubility 
SOLUBLE
λmax
280nm(EtOH)(lit.)
BRN 
106910
InChIKey
PEEHTFAAVSWFBL-UHFFFAOYSA-N
CAS DataBase Reference
541-59-3(CAS DataBase Reference)
NIST Chemistry Reference
1H-pyrrole-2,5-dione(541-59-3)
EPA Substance Registry System
1H-Pyrrole-2,5-dione (541-59-3)
More
Less

Safety

Hazard Codes 
T,C
Risk Statements 
25-34-43-36/37/38-36
Safety Statements 
26-36/37/39-45-37/39-28A-7/9
RIDADR 
UN 2923 8/PG 2
WGK Germany 
3
RTECS 
ON4800000
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29251995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129585
Product name
Maleimide
Purity
99%
Packaging
2g
Price
$40.4
Updated
2024/03/01
Sigma-Aldrich
Product number
129585
Product name
Maleimide
Purity
99%
Packaging
10g
Price
$118
Updated
2024/03/01
TCI Chemical
Product number
M0018
Product name
Maleimide
Purity
>98.0%(T)
Packaging
5g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
M0018
Product name
Maleimide
Purity
>98.0%(T)
Packaging
25g
Price
$190
Updated
2024/03/01
Alfa Aesar
Product number
A13135
Product name
Maleimide, 98+%
Packaging
5g
Price
$58.8
Updated
2024/03/01
More
Less

Maleimide Chemical Properties,Usage,Production

Chemical Properties

slight yellow crystalline powder

Uses

Reacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry.

Uses

Rhodium-catalyzed conjugate arylation with arylboronic acids.1

Definition

ChEBI: A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure.

General Description

Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.

Hazard

A poison.

Safety Profile

Poison by intraperitoneal and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify it by sublimation in a vacuum. The UV has max at 216 and 280nm in EtOH. [de Wolf & van de Straete Bull Soc Chim Belg 44 288 1935, UV: Rondestvedt et al. J Am Chem Soc 78 6115 1956, IR: Chiorboli & Mirone Ann Chim (Rome) 42 681 1952, Beilstein 21/10 V 3.]

Maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Maleimide Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
More
Less

View Lastest Price from Maleimide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Maleimide 541-59-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98.0%
Supply Ability
1kg/month
Release date
2023-02-13
Hebei Mojin Biotechnology Co., Ltd
Product
Maleimide 541-59-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-06
Hebei Guanlang Biotechnology Co,.LTD
Product
Maleimide 541-59-3
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2022-01-25

541-59-3, MaleimideRelated Search:


  • MaleiMide, 98% 10GR
  • MaleiMide, 98% 25GR
  • 2,5-Dioxo-2,5-dihydropyrrole
  • NSC 13684
  • 1H-Pyrrole-2,5-dione, 2,5-Dihydro-2,5-dioxo-1H-pyrrole
  • MaleiMide 99%
  • 5-hydroxy-2H-pyrrol-2-one
  • PYRROLE-2,5-DIONE
  • 2,5-Dioxo-3-pyrroline~1H-Pyrrole-2,5-dione
  • 3-Pyrroline-2,5-dione
  • Maleic imide
  • maleicimide
  • Maleinimide
  • MALEIMIDE
  • MALEIC ACID IMIDE
  • ASISCHEM S97810
  • 1h-pyrrole-2,5-dione
  • 2,5-PYRROLEDIONE
  • Maleimide, 98+%
  • 2,5-dioxo-3-pyrroline
  • 1H-Pyrrole-2,5-dione,2,5-Pyrroledione
  • Maleimide,90-95%
  • Maleimide&gt
  • Maleimide, 98%, for synthesis
  • potassium silver(1+) bis(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-ide)
  • Maleinseureimid
  • 541-59-3
  • 41-59-3
  • AMINE
  • Cyclic Imides
  • Organic Building Blocks
  • Carbonyl Compounds
  • Building Blocks
  • Miscellaneous Reagents
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Cyclic Imides
  • Organic Building Blocks
  • MTS & Sulfhydryl Active Reagents
  • Heterocycles series
  • Heterocycles