Mal-Amido-PEG4-acid

Product Name: Mal-Amido-PEG4-acid
CAS No.: 1263045-16-4
Chemical Name: Mal-Amido-PEG4-acid
Synonyms: BMPA-PEG4-Acid;Mal-NH-PEG4-COOH;Mal-NH-PEG4-acid;Mal-Amido-PEG4-acid;MAL-AMIDO-PEG4-COOH;Mal-dPEG4-CH2CH2COOH;Mal-NH-PEG4-CH2CH2COOH;MAL-dPEG??-acid (QBD-10338);Maleimide-NH-PEG4-CH2CH2COOH;Mal-amido-PEG4-propionic acid
CBNumber: CB03062522
Molecular Formula: C18H28N2O9
Formula Weight: 416.42
MOL File: 1263045-16-4.mol

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Mal-Amido-PEG4-acid Property

Boiling point:: 659.1±55.0 °C(Predicted)
Density: 1.270±0.06 g/cm3(Predicted)
storage temp.: -20°C, protect from light
solubility: Soluble in Water, DMSO, DMF, DCM
pka: 4.28±0.10(Predicted)
form: powder to crystal
color: White to Gray to Brown
InChI: InChI=1S/C18H28N2O9/c21-15(3-6-20-16(22)1-2-17(20)23)19-5-8-27-10-12-29-14-13-28-11-9-26-7-4-18(24)25/h1-2H,3-14H2,(H,19,21)(H,24,25)
InChIKey: IAJVEYLYYHOZEY-UHFFFAOYSA-N
SMILES: C(O)(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
CAS DataBase Reference: 1263045-16-4

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Safety

HS Code: 3822000000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2666
Product name: 19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid
Purity: >95.0%(HPLC)
Packaging: 25mg
Price: $55
Updated: 2025/07/31

TCI Chemical

Product number: M2666
Product name: 19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid
Purity: >95.0%(HPLC)
Packaging: 100mg
Price: $154
Updated: 2025/07/31

TRC

Product number: M157503
Product name: 19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Chem-Impex

Product number: 39665
Product name: 19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoicacid,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 25MG
Price: $63.84
Updated: 2021/12/16

dPEG

Product number: 10338
Product name: MAL-dPEG®₄-acid
Packaging: 1000mg
Price: $125
Updated: 2021/12/16

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Mal-Amido-PEG4-acid Chemical Properties,Usage,Production

Description

Mal-amido-PEG4-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-amido-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Mal-Amido-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-Amido-PEG4-acid Suppliers

Americas 1 China 80 Europe 1 India 1 Japan 1 United Kingdom 1 United States 8 Global 93

Hangzhou HanLai Biochemical Technology Co., Ltd.

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Tongling HengYou Biotechnology Co., Ltd.

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View Lastest Price from Mal-Amido-PEG4-acid manufacturers

LAURENT

Product: Mal-NH-PEG4-CH2CH2COOH 1263045-16-4
Price: US $465.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-15

Xian confluore Biological Technology Co., Ltd.

Product: Mal-amido-PEG4-acid 1263045-16-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-27

1263045-16-4, Mal-Amido-PEG4-acidRelated Search:

alpha-MaleiMidopropionyl-oMega-succiniMidyl-10(ethylene glycol) alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) Mal-PEG2-amine Mal-PEG3-NHS ester Mal-PEG6-COOH N-Succinimidyl 3-maleimidopropionate Mal-PEG4-NHS ester 3,4-Dibromo-Mal-PEG2-Amine Maleimido-Tri(Ethylene Glycol)-Propionic Acid Mal-PEG2-COOH N-[4-(-Carboxycyclohexylmethyl)]maleimide Mal-PEG4-Acid Mal-PEG2-NHS ester Bis-Mal-Lysine-PEG4-TFP ester Maleimide-PEG4-NHS Ester Maleimide-PEG2-NHS Ester 3-Maleimidopropionic acid Mal-PEG2-acid

Mal-CH2CH2CONH-PEG4-CH2CH2COOH

1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12-tetraoxapentadecan-15-oic acid

19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid

Maleimide-NH-PEG4-CH2CH2COOH

Maleimide-PEG4-propionic acid

MAL-AMIDO-PEG4-COOH

Mal-NH-PEG4-COOH

Mal-Amido-PEG4-acid

Mal-NH-PEG4-acid

4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-

Mal-amido-PEG4-propionic acid

1-Maleimido-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oic Acid

1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oic acid

BMPA-PEG4-Acid

Mal-CH2CH2CONH-PEG4-CH2CH2COOH/4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-

3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Mal-dPEG4-CH2CH2COOH

MAL-dPEG??-acid (QBD-10338)

3-Amino(peg4)propionic acid 3-maleimidopropionamide

Mal-NH-PEG4-CH2CH2COOH

1263045-16-4

C18H28N2O9

peg