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Maleimide-PEG4-NHS Ester

Product Name
Maleimide-PEG4-NHS Ester
CAS No.
756525-99-2
Chemical Name
Maleimide-PEG4-NHS Ester
Synonyms
Mal-PEG4-NHS;Mal-NH-PEG4-NHS;2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate;Mal-amido-PEG4-NHS;N-Succinim;Mal-PEG4-SPA;MAL-DPEG4-NHS Ester;BMPA-PEG4-NHS Ester;Mal-NH-PEG4-NHS ester;Maleimide-PEG4-NHS Ester
CBNumber
CB22546917
Molecular Formula
C22H31N3O11
Formula Weight
513.49
MOL File
756525-99-2.mol
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Maleimide-PEG4-NHS Ester Property

Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO
form 
Solid
pka
15.01±0.46(Predicted)
color 
White to off-white
InChI
InChI=1S/C22H31N3O11/c26-17(5-8-24-18(27)1-2-19(24)28)23-7-10-33-12-14-35-16-15-34-13-11-32-9-6-22(31)36-25-20(29)3-4-21(25)30/h1-2H,3-16H2,(H,23,26)
InChIKey
XSRYGQJQNPJNKZ-UHFFFAOYSA-N
SMILES
C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
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Safety

WGK Germany 
3
HS Code 
2928009090
Storage Class
10 - Combustible liquids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
712582
Product name
O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol
Purity
≥90% (NMR)
Packaging
100mg
Price
$476
Updated
2026/03/19
TCI Chemical
Product number
M2185
Product name
Maleimide-PEG4-NHS Ester
Packaging
50MG
Price
$111
Updated
2026/03/19
TCI Chemical
Product number
M2185
Product name
Maleimide-PEG4-NHS Ester
Packaging
250MG
Price
$377
Updated
2026/03/19
TRC
Product number
T889795
Product name
Maleimide-PEG4-NHS
Packaging
100mg
Price
$220
Updated
2021/12/16
BroadPharm
Product number
BP-22157
Product name
Mal-amido-PEG4-NHS
Purity
95%
Packaging
1g
Price
$255
Updated
2021/12/16
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Maleimide-PEG4-NHS Ester Chemical Properties,Usage,Production

Description

Mal-amido-PEG4-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Maleimide-PEG4-NHS (CAS# 756525-99-2) is a cross-linking compound used in the lysosomal acid-triggered release of anticancer drugs.

reaction suitability

reagent type: cross-linking reagent

IC 50

PEGs; Alkyl/ether

Maleimide-PEG4-NHS Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Maleimide-PEG4-NHS Ester Suppliers

Shanghai ruichang pharmaceutical technology co., LTD
Tel
18621054990
Email
maychemicals@sina.com
Country
China
ProdList
673
Advantage
58
ChemPep, Inc.
Tel
+1 (888) 615-9178 / (561) 791-8787
Fax
+1 (561) 791-8728
Email
service@chempep.com
Country
United States
ProdList
2138
Advantage
57
Chengdu Pukang Biotechnology Co., Ltd
Tel
15680681408 18217049878
Fax
086-28-82550468
Email
cassie.gao@pu-kang.com
Country
China
ProdList
468
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
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58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9520
Advantage
58
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39999
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5873
Advantage
58
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View Lastest Price from Maleimide-PEG4-NHS Ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
MAL-amido-PEG4-NHS 756525-99-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-06
LAURENT
Product
Mal-NH-PEG4-CH2CH2COONHS ester 756525-99-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2026-01-29
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate 756525-99-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-24

756525-99-2, Maleimide-PEG4-NHS EsterRelated Search:


  • alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol)
  • N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide
  • O-[N-(3-MaleiMidopropionyl)aMinoethyl]-O′-[3-(N-succiniMidyloxy)-3-oxopropyl]triethylene glycol
  • O-[N-(3-Maleimidopropionyl)aminoethyl]-O'-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol >=90% (NMR)
  • Mal-amido-PEG4-NHS
  • MAL-DPEG4-NHS Ester
  • 3-(2-Maleimidoethylcarbamoyl)-peg4-propionic acid N-hydroxysuccinimide ester
  • Maleimide-NH-PEG4-CH2CH2COONHS Ester
  • Maleimide-PEG4-NHS Ester
  • 2,5-dioxopyrrolidin-1-yl 19-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-17-oxo-4,7,10,13-tetraoxa-16-azanonadecan-1-oate
  • Maleimidopropionyl-PEG4-CH2CH2COONHS Ester
  • MAL-NH-PEG4-CH2CH2COONHS
  • Mal-NH-PEG4-NHS
  • Mal-NH-PEG4-NHS ester
  • 4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • Maleimide-PEG4-succinimidyl Ester
  • N-Succinim
  • BMPA-PEG4-NHS Ester
  • Mal-amido-PEG-4-NHS ester,Mal amido PEG4 NHS ester,PROTAC Linkers,MalamidoPEG4NHS ester,inhibit,Inhibitor
  • Mal-CH2CH2CONH-PEG4-CH2CH2COONHS
  • O-[<i>N</i>-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(<i>N</i>-succinimidyloxy)-3-oxopropyl]triethylene glycol
  • MAL-dPEG??-NHS ester (QBD-10214)
  • Bis-MAL-dPEG?? (QBD-10215)
  • N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanam
  • monodisperse Mal-PEG4-NHS-ester
  • monodisperse Mal-PEG4-NHS-ester, CAS 756525-99-2
  • 2,5-Dioxo-1-pyrrolidinyl 1-(2,5-dioxo-2,5-dihydro-1-pyrrolyl)-3-oxo-7,10,13,16-tetraoxa-4-aza-19-nonadecanoate
  • Mal-NH-PEG4-CH2CH2COONHS ester
  • Mal-PEG4-SPA
  • Amido Mal-PEG4-NHS Ester
  • 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate
  • Mal-PEG4-NHS
  • 756525-99-2
  • peg