ChemicalBook > CAS DataBase List > HO-PEG5-tBu

HO-PEG5-tBu

Product Name
HO-PEG5-tBu
CAS No.
850090-09-4
Chemical Name
HO-PEG5-tBu
Synonyms
tert-Butyl 1-hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oate;HO-PEG5-CH2CH2COOtBu;HO-PEG5-COOtBu;OH-PEG5-CH2CH2COOtBu;OH-PEG5-TBA;HO-PEG5-tBu;Hydroxy-PEG5-Boc;HO-PEG?-CH?CH?COOtBu;Hydroxy-PEG5-CH2CO2tBu;HO-PEG5-CH2CH2COOt<
CBNumber
CB12546899
Molecular Formula
C17H34O8
Formula Weight
366.45
MOL File
850090-09-4.mol
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HO-PEG5-tBu Property

Boiling point:
445.4±40.0 °C(Predicted)
Density 
1.071
refractive index 
n/D 1.448
storage temp. 
-20°C
form 
liquid
pka
14.36±0.10(Predicted)
color 
Colorless to light yellow
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902691
Product name
Hydroxy-PEG5-t-butyl ester
Packaging
250mg
Price
$257
Updated
2023/06/20
Sigma-Aldrich
Product number
902691
Product name
Hydroxy-PEG5-t-butyl ester
Packaging
1g
Price
$757
Updated
2023/06/20
BroadPharm
Product number
BP-20445
Product name
Hydroxy-PEG5-t-butyl ester
Purity
98%
Packaging
10g
Price
$825
Updated
2021/12/16
Activate Scientific
Product number
AS103979
Product name
HO-PEG5-CH2CH2COOtBu
Purity
95+%
Packaging
5G
Price
$897
Updated
2021/12/16
AK Scientific
Product number
0461AP
Product name
HO-PEG5-tBu
Packaging
5g
Price
$996
Updated
2021/12/16
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HO-PEG5-tBu Chemical Properties,Usage,Production

Description

Hydroxy-PEG5-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

HO-PEG5-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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HO-PEG5-tBu Suppliers

PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
ChemPep, Inc.
Tel
+1 (888) 615-9178 / (561) 791-8787
Fax
+1 (561) 791-8728
Email
service@chempep.com
Country
United States
ProdList
2138
Advantage
57
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Nanjing Anyan Pharmaceutical Technology Co. , Ltd.
Tel
025-58361178 17351780683
Fax
QQ3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
356
Advantage
60
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Shanghai Boka-chem Tech. Inc.
Tel
400-026-1533/(021) 6478-0600
Fax
+86 (21) 6459-2060
Email
sales@bokachem.com
Country
China
ProdList
876
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
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View Lastest Price from HO-PEG5-tBu manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Hydroxy-PEG5-t-butyl ester 850090-09-4
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25
Career Henan Chemical Co
Product
HO-PEG5-tBu 850090-09-4
Price
US $2.00/g
Min. Order
1g
Purity
95~99.9%
Supply Ability
5KG
Release date
2020-03-05

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