HO-PEG5-tBu
- Product Name
- HO-PEG5-tBu
- CAS No.
- 850090-09-4
- Chemical Name
- HO-PEG5-tBu
- Synonyms
- tert-Butyl 1-hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oate;HO-PEG5-CH2CH2COOtBu;HO-PEG5-COOtBu;OH-PEG5-CH2CH2COOtBu;OH-PEG5-TBA;HO-PEG5-tBu;Hydroxy-PEG5-Boc;HO-PEG?-CH?CH?COOtBu;Hydroxy-PEG5-CH2CO2tBu;Hydroxy-PEG5-t-butly ester
- CBNumber
- CB12546899
- Molecular Formula
- C17H34O8
- Formula Weight
- 366.45
- MOL File
- 850090-09-4.mol
HO-PEG5-tBu Property
- Boiling point:
- 445.4±40.0 °C(Predicted)
- Density
- 1.071
- refractive index
- n/D 1.448
- storage temp.
- -20°C
- form
- liquid
- pka
- 14.36±0.10(Predicted)
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 902691
- Product name
- Hydroxy-PEG5-t-butyl ester
- Packaging
- 250mg
- Price
- $257
- Updated
- 2023/06/20
- Product number
- 902691
- Product name
- Hydroxy-PEG5-t-butyl ester
- Packaging
- 1g
- Price
- $757
- Updated
- 2023/06/20
- Product number
- BP-20445
- Product name
- Hydroxy-PEG5-t-butyl ester
- Purity
- 98%
- Packaging
- 10g
- Price
- $825
- Updated
- 2021/12/16
- Product number
- AS103979
- Product name
- HO-PEG5-CH2CH2COOtBu
- Purity
- 95+%
- Packaging
- 5G
- Price
- $897
- Updated
- 2021/12/16
- Product number
- 0461AP
- Product name
- HO-PEG5-tBu
- Packaging
- 5g
- Price
- $996
- Updated
- 2021/12/16
HO-PEG5-tBu Chemical Properties,Usage,Production
Description
Hydroxy-PEG5-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
HO-PEG5-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
HO-PEG5-tBu Suppliers
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- 400-0255188 4000255188
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- 400-026-1533/(021) 6478-0600
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- Country
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View Lastest Price from HO-PEG5-tBu manufacturers
- Product
- Hydroxy-PEG5-t-butyl ester 850090-09-4
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25
- Product
- HO-PEG5-tBu 850090-09-4
- Price
- US $2.00/g
- Min. Order
- 1g
- Purity
- 95~99.9%
- Supply Ability
- 5KG
- Release date
- 2020-03-05