ChemicalBook > CAS DataBase List > HO-PEG5-tBu

HO-PEG5-tBu

Product Name
HO-PEG5-tBu
CAS No.
850090-09-4
Chemical Name
HO-PEG5-tBu
Synonyms
tert-Butyl 1-hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oate;HO-PEG5-CH2CH2COOtBu;HO-PEG5-COOtBu;OH-PEG5-CH2CH2COOtBu;OH-PEG5-TBA;HO-PEG5-tBu;Hydroxy-PEG5-Boc;HO-PEG?-CH?CH?COOtBu;Hydroxy-PEG5-CH2CO2tBu;HO-PEG5-CH2CH2COOt<
CBNumber
CB12546899
Molecular Formula
C17H34O8
Formula Weight
366.45
MOL File
850090-09-4.mol
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HO-PEG5-tBu Property

Boiling point:
445.4±40.0 °C(Predicted)
Density 
1.071
refractive index 
n/D 1.448
storage temp. 
-20°C
form 
liquid
pka
14.36±0.10(Predicted)
color 
Colorless to light yellow
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902691
Product name
Hydroxy-PEG5-t-butyl ester
Packaging
250mg
Price
$257
Updated
2023/06/20
Sigma-Aldrich
Product number
902691
Product name
Hydroxy-PEG5-t-butyl ester
Packaging
1g
Price
$757
Updated
2023/06/20
BroadPharm
Product number
BP-20445
Product name
Hydroxy-PEG5-t-butyl ester
Purity
98%
Packaging
10g
Price
$825
Updated
2021/12/16
Activate Scientific
Product number
AS103979
Product name
HO-PEG5-CH2CH2COOtBu
Purity
95+%
Packaging
5G
Price
$897
Updated
2021/12/16
AK Scientific
Product number
0461AP
Product name
HO-PEG5-tBu
Packaging
5g
Price
$996
Updated
2021/12/16
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HO-PEG5-tBu Chemical Properties,Usage,Production

Description

Hydroxy-PEG5-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

HO-PEG5-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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HO-PEG5-tBu Suppliers

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View Lastest Price from HO-PEG5-tBu manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Hydroxy-PEG5-t-butyl ester 850090-09-4
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25
Career Henan Chemical Co
Product
HO-PEG5-tBu 850090-09-4
Price
US $2.00/g
Min. Order
1g
Purity
95~99.9%
Supply Ability
5KG
Release date
2020-03-05

850090-09-4, HO-PEG5-tBuRelated Search:

Hydroxy-PEG4-methyl ester 4-MALEIMIDOBUTYRIC ACID 2-[2-(2-Azidoethoxy)ethoxy]ethanamine 2,5,8,11,14,17,20,23-Octaoxapentacosane-25-thiol 2-[2-(2-methoxyethoxy)ethoxy]-ethanethiol 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester FMoc-NH-PEG9-CH2CH2COOH Decaethylene glycol FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Biotin-PEG3-N3 H2N-PEG4-tBu 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine Amino-PEG6-alcohol FMoc-NH-5(ethylene glycol)-acetic acid Fmoc-NH-PEG3-CH2COOH 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) HS-PEG4-tBu

  • 1-Hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oic acid 1,1-dimethylethyl ester
  • HO-PEG5-CH2CH2COOtBu
  • HO-PEG<sub>5</sub>-CH<sub>2</sub>CH<sub>2</sub>COO<sup>t</sup>Bu
  • Hydroxy-PEG5-CH2CO2tBu
  • HO-PEG5-tBu
  • OH-PEG5-CH2CH2COOtBu
  • OH-PEG5-TBA
  • 2-METHYL-2-PROPANYL 1-HYDROXY-3,6,9,12,15-PENTAOXAOCTADECAN-18-OA TE
  • Hydroxy-PEG5-t-butly ester
  • tert-Butyl 1-hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oate
  • HO-PEG5-COOtBu
  • Hydroxy-PEG5-Boc
  • 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-hydroxy-, 1,1-dimethylethyl ester
  • HO-PEG?-CH?CH?COOtBu
  • PROTAC Linkers,Inhibitor,Hydroxy-PEG-5-Boc,inhibit,HydroxyPEG5Boc,Hydroxy PEG5 Boc
  • HO-PEG5-CH2CH2COOtBu / 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-hydroxy-, 1,1-dimethylethyl ester
  • tert-butyl 3-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • HO-PEG5-CH2CH2COO<sup>t<
  • 850090-09-4
  • C17H34O8
  • peg