N-[4-(-Carboxycyclohexylmethyl)]maleimide

Product Name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
CAS No.: 64987-82-2
Chemical Name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Synonyms: Mal-Cyclohexanecarboxylicacid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl);4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid;4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95%;4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid;4-(Maleimidomethyl)cyclohexanecarboxylic Acid (Discontinued, see C177860);4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid;Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-;4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid
CBNumber: CB41176520
Molecular Formula: C12H15NO4
Formula Weight: 237.25
MOL File: 64987-82-2.mol

More

Less

N-[4-(-Carboxycyclohexylmethyl)]maleimide Property

Melting point:: 157-158°C
Boiling point:: 433.6±18.0 °C(Predicted)
Density: 1.329±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform, Methanol
form: Solid
pka: 4.80±0.10(Predicted)
color: Pale Yellow
InChI: InChI=1S/C12H15NO4/c14-10-5-6-11(15)13(10)7-8-1-3-9(4-2-8)12(16)17/h5-6,8-9H,1-4,7H2,(H,16,17)
InChIKey: LQILVUYCDHSGEU-UHFFFAOYSA-N
SMILES: C1(C(O)=O)CCC(CN2C(=O)C=CC2=O)CC1

More

Less

Safety

HS Code: 2925.19.9100

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: M3218
Product name: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
Packaging: 1G
Price: $234
Updated: 2024/03/01

TCI Chemical

Product number: M3218
Product name: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
Packaging: 5G
Price: $819
Updated: 2024/03/01

TRC

Product number: C177860
Product name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Packaging: 25mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC19767
Product name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Packaging: 5G
Price: $150
Updated: 2021/12/16

AK Scientific

Product number: J95578
Product name: N-[4-(-Carboxycyclohexylmethyl)]maleimide
Packaging: 250mg
Price: $160
Updated: 2021/12/16

More

Less

N-[4-(-Carboxycyclohexylmethyl)]maleimide Chemical Properties,Usage,Production

Description

4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical Properties

White Solid

Uses

A sulfhydryl crosslinking reagent.

Uses

An amino reactive reagent.

Definition

N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.

N-[4-(-Carboxycyclohexylmethyl)]maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-[4-(-Carboxycyclohexylmethyl)]maleimide Suppliers

Americas 1 Canada 2 China 64 Europe 1 India 3 Japan 1 United Kingdom 3 United States 8 Global 83

Suzhouhongxiong

Tel: 18051745768 18051745768
Email: Suzhouhongxiong@163.com
Country: China
ProdList: 100
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44700
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
Advantage: 66

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8613162137806 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
Country: China
ProdList: 9742
Advantage: 57

Chengdu Pukang Biotechnology Co., Ltd

Tel: 028-82550498 19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 485
Advantage: 58

China Kouting Group Limited

Tel: +86 (21) 5811-6473 5811-6475
Fax: +86 (21) 6129-4103
Email: sales@koutingchina.com
Country: China
ProdList: 496
Advantage: 60

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28398
Advantage: 80

More

Less

View Lastest Price from N-[4-(-Carboxycyclohexylmethyl)]maleimide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Mal-Cyclohexanecarboxylicacid 64987-82-2
Price: US $0.00/g
Min. Order: 25g
Purity: >95.00%
Supply Ability: 25g
Release date: 2024-03-27

64987-82-2, N-[4-(-Carboxycyclohexylmethyl)]maleimideRelated Search:

Maleimido-Tri(Ethylene Glycol)-Propionic Acid Mal-PEG2-COOH Mal-PEG4-Acid Mal-PEG2-NHS ester Bis-Mal-Lysine-PEG4-TFP ester Maleimide-PEG4-NHS Ester Maleimide-PEG2-NHS Ester 3-Maleimidopropionic acid Mal-PEG2-acid Mal-Amido-PEG4-acid 2-MALEIMIDOETHYLAMINE HCL 4-MALEIMIDOBUTYRIC ACID 1h-pyrrole-2,5-dione, 1-[2-(2-aminoethoxy)ethyl]-, 2,2,2-trifluoroacetate (1:1) Maleimide-SS-amine Deruxtecan SMCC crosslinker SULFO-SMCC N-[4-(-Carboxycyclohexylmethyl)]maleimide

4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid

4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95%

4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid

4-(Maleimidomethyl)cyclohexanecarboxylic Acid (Discontinued, see C177860)

4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid

4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid

4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)

4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid

Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-

Mal-Cyclohexanecarboxylicacid

64987-82-2

Cross Linking Reagents

Maleimide Derivatives

MTS & Sulfhydryl Active Reagents

satralizumab-linker