3,4-Dibromo-Mal-PEG2-Amine

Product Name: 3,4-Dibromo-Mal-PEG2-Amine
CAS No.: 1807534-86-6
Chemical Name: 3,4-Dibromo-Mal-PEG2-Amine
Synonyms: 3,4-Dibromo-Mal-PEG2-Amine;3,4-Dibromo-Mal-PEG2-Amine TFA salt;1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-3,4-dibromo-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-3,4-dibromo-
CBNumber: CB63062276
Molecular Formula: C10H14Br2N2O4
Formula Weight: 386.04
MOL File: 1807534-86-6.mol

More

Less

3,4-Dibromo-Mal-PEG2-Amine Property

Boiling point:: 425.1±45.0 °C(Predicted)
Density: 1.831±0.06 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 8.74±0.10(Predicted)

More

Less

Safety

HS Code: 2933998090

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-22011
Product name: 3,4-Dibromo-Mal-PEG2-AmineTFAsalt
Purity: 98%
Packaging: 250mg
Price: $390
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1378
Product name: 3,4-Dibromo-Mal-PEG2-Amine
Packaging: 100mg
Price: $449
Updated: 2021/12/16

BroadPharm

Product number: BP-22011
Product name: 3,4-Dibromo-Mal-PEG2-AmineTFAsalt
Purity: 98%
Packaging: 1g
Price: $870
Updated: 2021/12/16

More

Less

3,4-Dibromo-Mal-PEG2-Amine Chemical Properties,Usage,Production

Description

3,4-Dibromo-Mal-PEG2-Amine TFA salt is a PEG linker containing a dibromomaleimide group and a primary amine. The dibromomaleimide group allows for two points of attachement because both of the bromine atoms can be substituted. The primary amine can react with carboxylic acids, activated NHS esters and other carbonyl compounds. PEG linkers are hydrophilic moieties, therefore the attachment of a PEG linker to a compound increases it's water solubility properties in aqueous media.

Uses

3,4-Dibromo-Mal-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

3,4-Dibromo-Mal-PEG2-Amine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3,4-Dibromo-Mal-PEG2-Amine Suppliers

China 24 India 1 United Kingdom 1 United States 3 Global 29

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
Fax: 027-59218822
Email: 3207347307@qq.com
Country: CHINA
ProdList: 1238
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1994
Advantage: 58

Shaanxi borno biotechnology co., LTD

Tel: +86-13759708231
Email: asherw9@hotmail.com
Country: China
ProdList: 2373
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Hangzhou Taorui Biotechnology Co., Ltd

Tel: 4000-360-990 15268198094
Email: sales@torreybio.com
Country: China
ProdList: 3806
Advantage: 58

1807534-86-6, 3,4-Dibromo-Mal-PEG2-AmineRelated Search:

Mal-PEG3-NHS ester Mal-PEG6-COOH N-Succinimidyl 3-maleimidopropionate Mal-PEG4-NHS ester Maleimido-Tri(Ethylene Glycol)-Propionic Acid Mal-PEG2-COOH N-[4-(-Carboxycyclohexylmethyl)]maleimide Mal-PEG4-Acid Mal-PEG2-NHS ester Bis-Mal-Lysine-PEG4-TFP ester Maleimide-PEG4-NHS Ester Maleimide-PEG2-NHS Ester 3-Maleimidopropionic acid Mal-PEG2-acid Mal-Amido-PEG4-acid 2-MALEIMIDOETHYLAMINE HCL 3,4-Dibromo-Mal-PEG2-Boc-Amine 3,4-Dibromo-Mal-PEG4-t-butyl ester

3,4-Dibromo-Mal-PEG2-Amine

3,4-Dibromo-Mal-PEG2-Amine TFA salt

1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-3,4-dibromo-

1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-3,4-dibromo-1H-pyrrole-2,5-dione

1807534-86-6

C10H14Br2N2O4