3,4-Dibromo-Mal-PEG2-Boc-Amine

Product Name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
CAS No.: 1807537-43-4
Chemical Name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Synonyms: 3,4-Dibromo-Mal-PEG2-NHBoc;3,4-Dibromo-Mal-PEG2-N-Boc;3,4-Dibromo-Mal-PEG2-Boc-Amine;tert-Butyl (2-(2-(2-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethyl)carbamate;Carbamic acid, N-[2-[2-[2-(3,4-dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester
CBNumber: CB93062277
Molecular Formula: C15H22Br2N2O6
Formula Weight: 486.15
MOL File: 1807537-43-4.mol

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3,4-Dibromo-Mal-PEG2-Boc-Amine Property

Boiling point:: 513.0±50.0 °C(Predicted)
Density: 1.609±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Solid
pka: 12.23±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22016
Product name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Purity: 98%
Packaging: 100mg
Price: $180
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1379
Product name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Packaging: 100mg
Price: $351
Updated: 2021/12/16

BroadPharm

Product number: BP-22016
Product name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Purity: 98%
Packaging: 500mg
Price: $510
Updated: 2021/12/16

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3,4-Dibromo-Mal-PEG2-Boc-Amine Chemical Properties,Usage,Production

Description

3,4-Dibromo-Mal-PEG2-Boc-Amine is a hydrophilic PEG species containing a dibromomaleimide group and a Boc-protected amine. The dibromomaleimide group allows for two points of attachement because both of the bromine atoms can be substituted. The Boc protecting group can be removed under acidic conditions and allows for the amine to further react with other species. The hydrophilic PEG linker increases the compound's water solubility properties in aqueous media.

Uses

3,4-Dibromo-Mal-PEG2-N-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

3,4-Dibromo-Mal-PEG2-Boc-Amine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Dibromo-Mal-PEG2-Boc-Amine Suppliers

China 25 United Kingdom 1 United States 4 Global 30

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
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Jinan elephant international trading co., LTD

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Email: 13006575422@163.com
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Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
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Xi'an Confluore Biological Technology Co., Ltd.

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Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
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TargetMol Chemicals Inc.

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Nextpeptide Inc

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Zhengzhou Akem Chemical Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
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View Lastest Price from 3,4-Dibromo-Mal-PEG2-Boc-Amine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: 3,4-Dibromo-Mal-PEG2-NHBoc 1807537-43-4
Price: US $0.00/g
Min. Order: 1g
Purity: >99.00%
Supply Ability: 1g
Release date: 2024-03-27

1807537-43-4, 3,4-Dibromo-Mal-PEG2-Boc-AmineRelated Search:

3,4-Dibromo-Mal-PEG4-t-butyl ester 3,4-Dibromo-Mal-PEG2-Amine

3,4-Dibromo-Mal-PEG2-Boc-Amine

3,4-Dibromo-Mal-PEG2-N-Boc

Carbamic acid, N-[2-[2-[2-(3,4-dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester

3,4-Dibromo-Mal-PEG2-NHBoc

tert-Butyl (2-(2-(2-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethyl)carbamate

1807537-43-4

C15H22Br2N2O6