3,4-Dibromo-Mal-PEG2-Boc-Amine

Product Name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
CAS No.: 1807537-43-4
Chemical Name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Synonyms: 3,4-Dibromo-Mal-PEG2-NHBoc;3,4-Dibromo-Mal-PEG2-N-Boc;3,4-Dibromo-Mal-PEG2-Boc-Amine;tert-Butyl (2-(2-(2-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethyl)carbamate;Carbamic acid, N-[2-[2-[2-(3,4-dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester
CBNumber: CB93062277
Molecular Formula: C15H22Br2N2O6
Formula Weight: 486.15
MOL File: 1807537-43-4.mol

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3,4-Dibromo-Mal-PEG2-Boc-Amine Property

Boiling point:: 513.0±50.0 °C(Predicted)
Density: 1.609±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Solid
pka: 12.23±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22016
Product name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Purity: 98%
Packaging: 100mg
Price: $180
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1379
Product name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Packaging: 100mg
Price: $351
Updated: 2021/12/16

BroadPharm

Product number: BP-22016
Product name: 3,4-Dibromo-Mal-PEG2-Boc-Amine
Purity: 98%
Packaging: 500mg
Price: $510
Updated: 2021/12/16

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3,4-Dibromo-Mal-PEG2-Boc-Amine Chemical Properties,Usage,Production

Description

3,4-Dibromo-Mal-PEG2-Boc-Amine is a hydrophilic PEG species containing a dibromomaleimide group and a Boc-protected amine. The dibromomaleimide group allows for two points of attachement because both of the bromine atoms can be substituted. The Boc protecting group can be removed under acidic conditions and allows for the amine to further react with other species. The hydrophilic PEG linker increases the compound's water solubility properties in aqueous media.

Uses

3,4-Dibromo-Mal-PEG2-N-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

3,4-Dibromo-Mal-PEG2-Boc-Amine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Dibromo-Mal-PEG2-Boc-Amine Suppliers

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View Lastest Price from 3,4-Dibromo-Mal-PEG2-Boc-Amine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: 3,4-Dibromo-Mal-PEG2-NHBoc 1807537-43-4
Price: US $0.00/g
Min. Order: 1g
Purity: >99.00%
Supply Ability: 1g
Release date: 2024-03-27

1807537-43-4, 3,4-Dibromo-Mal-PEG2-Boc-AmineRelated Search:

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3,4-Dibromo-Mal-PEG2-Boc-Amine

3,4-Dibromo-Mal-PEG2-N-Boc

Carbamic acid, N-[2-[2-[2-(3,4-dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester

3,4-Dibromo-Mal-PEG2-NHBoc

tert-Butyl (2-(2-(2-(3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethyl)carbamate

1807537-43-4

C15H22Br2N2O6