TN ANTIGEN

Product Name: TN ANTIGEN
CAS No.: 67262-86-6
Chemical Name: TN ANTIGEN
Synonyms: TN ANTIGEN;TN EPITOPE;Ser(α-D-GalNHAc)-OH;GALNAC-ALPHA1-O-SER;GalNac-α-1-O-serine;Olanzapine Impurity 50;Galactose Impurity 9 (Tn Epitope);N-ACETYLGALACTOSAMINE, ALPHA1-O-SERINE;N-Acetyl-α-D-galactosaMinyl- 1-O-serine;N-ACETYL-ALPHA-D-GALACTOSAMINYL-1-O-SERINE
CBNumber: CB3283024
Molecular Formula: C11H20N2O8
Formula Weight: 308.29
MOL File: Mol file

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TN ANTIGEN Property

Melting point:: 198-201°C
Boiling point:: 701.2±60.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Water
form: Solid
pka: 2.05±0.10(Predicted)
color: Off-White to Yellow
Stability:: HYGROSCOPIC

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 53886
Product name: Tn Antigen
Purity: ≥99.0% (TLC)
Packaging: 1mg
Price: $404
Updated: 2024/03/01

Usbiological

Product number: T2660-30
Product name: Tn Epitope
Packaging: 1mg
Price: $375
Updated: 2021/12/16

TRC

Product number: T020050
Product name: TnEpitope
Packaging: 5mg
Price: $450
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: ATG0000871
Product name: Tn Antigen
Purity: 95.00%
Packaging: 1MG
Price: $673.08
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MA07378
Product name: 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine
Packaging: 5mg
Price: $425
Updated: 2021/12/16

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TN ANTIGEN Chemical Properties,Usage,Production

Chemical Properties

TN ANTIGEN is Yellow Solid

Uses

TN ANTIGEN is a cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines

Uses

A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines.

Definition

ChEBI: O-(N-acetyl-alpha-D-galactosaminyl)-L-serine is a non-proteinogenic L-amino acid that is N-acetyl-alpha-D-galactosamine linked via an alpha glycosidic bond to the O at position 3 of L-serine. It has a role as a tumour antigen. It is a L-serine derivative and a non-proteinogenic L-alpha-amino acid.

General Description

Tn antigen?is a truncated O-glycan, that is commonly noticed in colorectal cancer (CRC). It is usually expressed at high levels in cancer cells. Tn antigen is small in size and simple in structure. It has a non-physiological glycan structure in humans, hence it may be identified as foreign by the immune system.

Biochem/physiol Actions

Tn antigen stimulates colorectal cancer metastasis through the activation of epithelial-mesenchymal transition, mediated by H-Ras. It acts as a precursor to several significant complex O-glycans. Subpopulations of blood cells in all lineages carrying the Tn antigen results in a hematological disorder called Tn syndrome.

TN ANTIGEN Preparation Products And Raw materials

Raw materials

Preparation Products

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TN ANTIGEN Suppliers

Canada 1 China 26 India 1 Japan 1 United Kingdom 6 United States 4 Global 39

Shenzhen Excellent Biomedical Technology Co., Ltd.

Tel: 18318671572
Email: 2850803126@qq.com
Country: China
ProdList: 4993
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

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Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
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Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
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Beijing OKA biological technology co., LTD

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Beijing Minruida Technology Co., Ltd.

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55896
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67262-86-6, TN ANTIGENRelated Search:

GALNAC-ALPHA1-O-SER

SERINYL 2-ACETAMIDO-2-DEOXY-A-GALACTOPYRANOSIDE

Ser(α-D-GalNHAc)-OH

N-ACETYLGALACTOSAMINE, ALPHA1-O-SERINE

N-ACETYL-ALPHA-D-GALACTOSAMINYL-1-O-SERINE

TN EPITOPE

TN ANTIGEN

Serinyl 2-acetamido-2-deoxy-a-galactopyranoside, N-acetyl-a-D-galactosaminyl-1-O-serine

Serinyl 2-acetamido-2-deoxy-α-galactopyranoside, N-acetyl-α-D-galactosaminyl-1-O-serine

O-[2-(Acetylamino)-2-deoxy-alpha-D-galactopyranosyl]-L-serine

2-Acetamido-2-deoxy-a-D-galactopyranosyl serine

N-Acetyl-α-D-galactosaMinyl- 1-O-serine

O-[2-(AcetylaMino)-2-deoxy-α-D-galactopyranosyl]-

Serinyl 2-AcetaMido-2-deoxy-α-galactopyranoside

GalNac-α-1-O-serine

O-[2-(Acetylamino)-2-deoxy-α-D-galactopyranosyl]-L-serine

L-Serine, O-[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-

Galactose Impurity 9 (Tn Epitope)

(S)-3-[[(2S,3R,4R,5R,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-2-aminopropanoic Acid

Olanzapine Impurity 50

67262-86-6

C11H20N2O8

Carbohydrates & Derivatives

Amino Acids & Derivatives

13C & 2H Sugars