TN ANTIGEN

Product Name: TN ANTIGEN
CAS No.: 67262-86-6
Chemical Name: TN ANTIGEN
Synonyms: TN ANTIGEN;TN EPITOPE;Ser(α-D-GalNHAc)-OH;GALNAC-ALPHA1-O-SER;GalNac-α-1-O-serine;Olanzapine Impurity 50;Tn Antigen: H-Ser(α-D-GalNAc)-OH;Galactose Impurity 9 (Tn Epitope);N-ACETYLGALACTOSAMINE, ALPHA1-O-SERINE;N-Acetyl-α-D-galactosaMinyl- 1-O-serine
CBNumber: CB3283024
Molecular Formula: C11H20N2O8
Formula Weight: 308.29
MOL File: Mol file

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TN ANTIGEN Property

Melting point:: 198-201°C
Boiling point:: 701.2±60.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Water
form: Solid
pka: 2.05±0.10(Predicted)
color: Off-White to Yellow
Stability:: HYGROSCOPIC

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 53886
Product name: Tn Antigen
Purity: ≥99.0% (TLC)
Packaging: 1mg
Price: $404
Updated: 2024/03/01

Usbiological

Product number: T2660-30
Product name: Tn Epitope
Packaging: 1mg
Price: $375
Updated: 2021/12/16

TRC

Product number: T020050
Product name: TnEpitope
Packaging: 5mg
Price: $450
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: ATG0000871
Product name: Tn Antigen
Purity: 95.00%
Packaging: 1MG
Price: $673.08
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MA07378
Product name: 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine
Packaging: 5mg
Price: $425
Updated: 2021/12/16

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TN ANTIGEN Chemical Properties,Usage,Production

Chemical Properties

TN ANTIGEN is Yellow Solid

Uses

TN ANTIGEN is a cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines

Uses

A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines.

Definition

ChEBI: O-(N-acetyl-alpha-D-galactosaminyl)-L-serine is a non-proteinogenic L-amino acid that is N-acetyl-alpha-D-galactosamine linked via an alpha glycosidic bond to the O at position 3 of L-serine. It has a role as a tumour antigen. It is a L-serine derivative and a non-proteinogenic L-alpha-amino acid.

General Description

Tn antigen?is a truncated O-glycan, that is commonly noticed in colorectal cancer (CRC). It is usually expressed at high levels in cancer cells. Tn antigen is small in size and simple in structure. It has a non-physiological glycan structure in humans, hence it may be identified as foreign by the immune system.

Biochem/physiol Actions

Tn antigen stimulates colorectal cancer metastasis through the activation of epithelial-mesenchymal transition, mediated by H-Ras. It acts as a precursor to several significant complex O-glycans. Subpopulations of blood cells in all lineages carrying the Tn antigen results in a hematological disorder called Tn syndrome.

TN ANTIGEN Preparation Products And Raw materials

Raw materials

Preparation Products

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TN ANTIGEN Suppliers

Canada 1 China 27 India 1 Japan 1 United Kingdom 6 United States 4 Global 40

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4674
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-010-010-62971590 18548936886
Fax: 010-62340519
Email: jack@oka-vip.com
Country: China
ProdList: 6897
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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
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BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
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Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

67262-86-6, TN ANTIGENRelated Search:

GALNAC-ALPHA1-O-SER

SERINYL 2-ACETAMIDO-2-DEOXY-A-GALACTOPYRANOSIDE

Ser(α-D-GalNHAc)-OH

N-ACETYLGALACTOSAMINE, ALPHA1-O-SERINE

N-ACETYL-ALPHA-D-GALACTOSAMINYL-1-O-SERINE

TN EPITOPE

TN ANTIGEN

Serinyl 2-acetamido-2-deoxy-a-galactopyranoside, N-acetyl-a-D-galactosaminyl-1-O-serine

Serinyl 2-acetamido-2-deoxy-α-galactopyranoside, N-acetyl-α-D-galactosaminyl-1-O-serine

O-[2-(Acetylamino)-2-deoxy-alpha-D-galactopyranosyl]-L-serine

2-Acetamido-2-deoxy-a-D-galactopyranosyl serine

N-Acetyl-α-D-galactosaMinyl- 1-O-serine

O-[2-(AcetylaMino)-2-deoxy-α-D-galactopyranosyl]-

Serinyl 2-AcetaMido-2-deoxy-α-galactopyranoside

GalNac-α-1-O-serine

O-[2-(Acetylamino)-2-deoxy-α-D-galactopyranosyl]-L-serine

L-Serine, O-[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-

Galactose Impurity 9 (Tn Epitope)

(S)-3-[[(2S,3R,4R,5R,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-2-aminopropanoic Acid

Tn Antigen: H-Ser(α-D-GalNAc)-OH

Olanzapine Impurity 50

67262-86-6

C11H20N2O8

Carbohydrates & Derivatives

Amino Acids & Derivatives

13C & 2H Sugars