ChemicalBook > CAS DataBase List > TRANS-4,5-DIHYDROXY-1,2-DITHIANE

TRANS-4,5-DIHYDROXY-1,2-DITHIANE

Product Name
TRANS-4,5-DIHYDROXY-1,2-DITHIANE
CAS No.
14193-38-5
Chemical Name
TRANS-4,5-DIHYDROXY-1,2-DITHIANE
Synonyms
CYCLO-DTT;NSC 663605;OXIDIZED DTT;Einecs 238-047-6;trans-1,2-dithiane-4,5-diol;(SS,RR)-CYCLO-DITHIOTHREITOL;rel-1,2-Dithiane-4β*,5α*-diol;(S,S:R,R)-CYCLO-DITHIOTHREITOL;trans-4,5-Dihydroxy-o-dithiane;trans-4,5-Dihydroxy-1,2-dithian
CBNumber
CB3286555
Molecular Formula
C4H8O2S2
Formula Weight
152.24
MOL File
14193-38-5.mol
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TRANS-4,5-DIHYDROXY-1,2-DITHIANE Property

Melting point:
130-132 °C(lit.)
Boiling point:
284.9±40.0 °C(Predicted)
Density 
1.531±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
13.28±0.40(Predicted)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D3511
Product name
trans-4,5-Dihydroxy-1,2-dithiane
Purity
≥99%
Packaging
1g
Price
$99.8
Updated
2024/03/01
Sigma-Aldrich
Product number
D3511
Product name
trans-4,5-Dihydroxy-1,2-dithiane
Purity
≥99%
Packaging
5g
Price
$400
Updated
2024/03/01
Sigma-Aldrich
Product number
D3511
Product name
trans-4,5-Dihydroxy-1,2-dithiane
Purity
≥99%
Packaging
100g
Price
$4060
Updated
2023/06/20
American Custom Chemicals Corporation
Product number
CHM0124679
Product name
TRANS-4,5-DIHYDROXY-1,2-DITHIANE
Purity
95.00%
Packaging
1G
Price
$642.57
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD29479
Product name
trans-4,5-Dihydroxy-1,2-dithiane
Packaging
5G
Price
$700
Updated
2021/12/16
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TRANS-4,5-DIHYDROXY-1,2-DITHIANE Chemical Properties,Usage,Production

Uses

trans-4,5-Dihydroxy-1,2-dithiane is used in preparation of 1,2-Dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions.

Definition

ChEBI: (4S,5S)-1,2-dithiane-4,5-diol is a trans-1,2-dithiane-4,5-diol. It is an enantiomer of a (4R,5R)-1,2-dithiane-4,5-diol.

General Description

trans-4,5-Dihydroxy-1,2-dithiane (oxidized dtt) is an intramolecular disulfide form of dithiothreitol. It is a strong reducing agent with an ability to elicit a molecular stress response by activating the stress-responsive genes.

TRANS-4,5-DIHYDROXY-1,2-DITHIANE Preparation Products And Raw materials

Raw materials

Preparation Products

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14193-38-5, TRANS-4,5-DIHYDROXY-1,2-DITHIANERelated Search:


  • (S,S:R,R)1,2-DITHIA-4,5-DIHYDROXYCYCLOHEXANE
  • (SS,RR) 1,2-DITHIA-4,5-DIHYDROXY-CYCLOHEXANE
  • (S,S:R,R)-CYCLO-DITHIOTHREITOL
  • (SS,RR)-CYCLO-DITHIOTHREITOL
  • OXIDIZED DTT
  • TRANS-4,5-DIHYDROXY-1,2-DITHIANE
  • CYCLO-DTT
  • trans-1,2-dithiane-4,5-diol
  • (SS,RR)-cyclo-Dithiothreitol, (SS,RR) 1,2-Dithia-4,5-dihydroxy-cyclohexane, trans-4,5-Dihydroxy-1,2-dithane
  • trans-1,2-Dithiane-4,5-diol, Oxidized DTT
  • rel-(4R*,5R*)-1,2-Dithiane-4,5-diol
  • rel-(4R*,5R*)-Tetrahydro-1,2-dithiin-4,5-diol
  • rel-1,2-Dithiane-4β*,5α*-diol
  • trans-4,5-Dihydroxy-1,2-dithian
  • trans-4,5-Dihydroxy-1,2-dithiane >=99%
  • Einecs 238-047-6
  • trans-4,5-Dihydroxy-1,2-dithiane,trans-1,2-Dithiane-4,5-diol, Oxidized DTT
  • NSC 663605
  • trans-4,5-Dihydroxy-o-dithiane
  • 1,2-Dithiane-4,5-diol, (4R,5R)-rel-
  • trans-4,5-Dihydroxy-1,2-dithane
  • 14193-38-5
  • Building Blocks
  • Heterocyclic Building Blocks
  • Others
  • S-Containing
  • Heterocyclic Compounds
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Others
  • S-Containing