ChemicalBook > CAS DataBase List > H-D-GLU(TRP-OH)-OH

H-D-GLU(TRP-OH)-OH

Product Name
H-D-GLU(TRP-OH)-OH
CAS No.
66471-20-3
Chemical Name
H-D-GLU(TRP-OH)-OH
Synonyms
Scv-07;Scv 07;Bestim;GLU-TRP;GAMMA-GLU-TRP;H-g-Glu-Trp-OH;H-γ-Glu-Trp-OH;H-GLU(TRP-OH)-OH;H-D-gGlu-L-Trp-OH;H-GAMMA-GLU-TRP-OH
CBNumber
CB3287734
Molecular Formula
C16H19N3O5
Formula Weight
333.34
MOL File
66471-20-3.mol
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H-D-GLU(TRP-OH)-OH Property

Boiling point:
737.3±60.0 °C(Predicted)
Density 
1.428
storage temp. 
−20°C
pka
2.22±0.10(Predicted)
Sequence
H-γ-Glu-Trp-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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H-D-GLU(TRP-OH)-OH Chemical Properties,Usage,Production

Uses

Bestim is a dipeptide, which exhibits high affinity to murine peritoneal macrophages, thymocytes, and plasma membranes isolated from these cells, with Kds of 3.1, 2.1, 18.6 and 16.7 nM, respectively. Bestim inhibits adenylate cyclase in the membranes of murine macrophages and thymocytes. Bestim exhibits immunomodulatory efficacy[1].

Definition

ChEBI: A glutamyl-L-amino acid obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of tryptophan.

References

[1] Kolobov AA, et al., Interaction of the synthetic immunomodulatory dipeptide bestim with murine macrophages and thymocytes. Bioorg Khim. 2008 Jan-Feb;34(1):43-9. Russian. DOI:10.1134/s1068162008010044

H-D-GLU(TRP-OH)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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66471-20-3, H-D-GLU(TRP-OH)-OHRelated Search:


  • GLU-TRP
  • GAMMA-GLU-TRP
  • H-D-GLU(TRP-OH)-OH
  • H-GAMMA-GLU-TRP-OH
  • H-GAMMA-D-GLU-TRP-OH
  • H-GLU(TRP-OH)-OH
  • Bestim
  • L-Tryptophan, L-gamma-glutamyl-
  • L-Tryptophan, N-L-gamma-glutamyl-
  • Scv 07
  • Scv-07
  • L-gamma-Glutamyl-L-tryptophan
  • H-g-Glu-Trp-OH
  • H-D-gGlu-L-Trp-OH
  • 2-amino-5-[[1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid
  • L-Tryptophan, L-g-glutamyl-
  • Bestim, 10 mM in DMSO
  • H-γ-Glu-Trp-OH
  • 66471-20-3
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Dipeptides
  • Dipeptides and Tripeptides
  • Dipeptides
  • Dipeptides and Tripeptides
  • Peptides