ChemicalBook > CAS DataBase List > H-D-GLU(TRP-OH)-OH
H-D-GLU(TRP-OH)-OH
- Product Name
- H-D-GLU(TRP-OH)-OH
- CAS No.
- 66471-20-3
- Chemical Name
- H-D-GLU(TRP-OH)-OH
- Synonyms
- Scv-07;Scv 07;Bestim;GLU-TRP;GAMMA-GLU-TRP;H-g-Glu-Trp-OH;H-γ-Glu-Trp-OH;H-GLU(TRP-OH)-OH;H-D-gGlu-L-Trp-OH;H-GAMMA-GLU-TRP-OH
- CBNumber
- CB3287734
- Molecular Formula
- C16H19N3O5
- Formula Weight
- 333.34
- MOL File
- 66471-20-3.mol
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H-D-GLU(TRP-OH)-OH Property
- Boiling point:
- 737.3±60.0 °C(Predicted)
- Density
- 1.428
- storage temp.
- −20°C
- pka
- 2.22±0.10(Predicted)
- Sequence
- H-γ-Glu-Trp-OH
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Safety
- WGK Germany
- 3
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H-D-GLU(TRP-OH)-OH Chemical Properties,Usage,Production
Uses
Bestim is a dipeptide, which exhibits high affinity to murine peritoneal macrophages, thymocytes, and plasma membranes isolated from these cells, with Kds of 3.1, 2.1, 18.6 and 16.7 nM, respectively. Bestim inhibits adenylate cyclase in the membranes of murine macrophages and thymocytes. Bestim exhibits immunomodulatory efficacy[1].
Definition
ChEBI: A glutamyl-L-amino acid obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of tryptophan.
References
[1] Kolobov AA, et al., Interaction of the synthetic immunomodulatory dipeptide bestim with murine macrophages and thymocytes. Bioorg Khim. 2008 Jan-Feb;34(1):43-9. Russian. DOI:10.1134/s1068162008010044
H-D-GLU(TRP-OH)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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H-D-GLU(TRP-OH)-OH Suppliers
- Tel
- --
- Fax
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- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
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