PRO0461
- Product Name
- PRO0461
- Chemical Name
- PRO0461
- Synonyms
- mPDK1;PDPK1;hPDK1;PRO0461;kinase PDK1;PDK1, active, His tagged human;3-phosphoinositide dependent protein kinase-1;Anti-PDK1, N-Terminal antibody produced in rabbit
- CBNumber
- CB32892877
- Formula Weight
- 0
- MOL File
- Mol file
PRO0461 Property
- storage temp.
- -70°C
- form
- buffered aqueous solution
- biological source
- rabbit
- Specific Activity
- 102-138nmol/min·mg
Safety
- WGK Germany
- nwg
- Storage Class
- 10 - Combustible liquids
N-Bromosuccinimide Price
- Product number
- SAB4502161
- Product name
- Anti-PDK1, N-Terminal antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μg
- Price
- $392
- Updated
- 2025/07/31
- Product number
- K3393
- Product name
- PDK1, active, His tagged human
- Purity
- PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
- Packaging
- 10μG
- Price
- $537
- Updated
- 2025/07/31
- Product number
- orb603326
- Product name
- PRO0461
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
- Product number
- orb597210
- Product name
- PDPK1
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
PRO0461 Chemical Properties,Usage,Production
Biological Activity
PDK1 (3-phosphoinositide-dependent protein kinase) is activated by the presence of PtdIns (3, 4, 5) P3 or PtdIns (3, 4) P2. PDK1 then activates protein kinase B (PKB) which, in turn, inactivates glycogen synthase kinase-3 (GSK3). The phosphorylation of other proteins by PKB and GSK3 is likely to mediate many of the intracellular actions of insulin. Thus, PDK1 plays a key role in mediating many of the actions of the second messenger(s) PtdIns (3, 4, 5) P3 and/or PtdIns (3, 4) P2. The human PDK1 is a 556-residue monomeric enzyme comprising of a catalytic domain th at is most similar to the PKA, PKB and PKC subfamily of protein kinases. ', 'PDPK1 (3-phosphoinositide dependent protein kinase 1) is a serine/threonine protein kinase which is activated upon accumulation of PIP3 (phosphatidylinositol-3,4,5-trisphosphate), a PI3K (phosphoinositide 3-kinase) product. It controls AGC (protein kinase A, G, and C) kinase members, such as AKT (v-akt murine thymoma viral oncogene homolog), p70 ribosomal S6 kinase (S6K), serum- and glucocorticoid-induced protein kinase (SGK), and protein kinase C (PKC) members. It is involved in metabolism, growth, proliferation, and survival. PDPK1 is associated with growth of angiosarcoma cells.
PRO0461 Preparation Products And Raw materials
Raw materials
Preparation Products
PRO0461 Suppliers
- Tel
- 021-60345367 13916550749
- sales@shzbio.com
- Country
- China
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- 9965
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- 027-87196173
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- China
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- 21-20338288
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- China
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- Tel
- 400-9019800
- sales@bioss.com.cn
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- China
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- 18859635977
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- CHINA
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- 19802084049
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- CHINA
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