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LANATOSIDE C

Product Name
LANATOSIDE C
CAS No.
17575-22-3
Chemical Name
LANATOSIDE C
Synonyms
Allocor;Celanid;isolanid;Ceglunat;Celanide;NSC 7533;isolanide;cedilanid;Ceglunate;Celadigal
CBNumber
CB3298279
Molecular Formula
C49H76O20
Formula Weight
985.12
MOL File
17575-22-3.mol
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LANATOSIDE C Property

Melting point:
272-274°C
alpha 
D20 +33.4 to +33.7° (200 mg dry weight in 10 ml alcohol)
Boiling point:
741.7°C (rough estimate)
Density 
1.42±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
1.7630 (estimate)
storage temp. 
-20°C
solubility 
DMSO:50.0(Max Conc. mg/mL);50.75(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);2.03(Max Conc. mM)
pka
12.89±0.70(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
LogP
0.070
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
OE2100000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H330Fatal if inhaled

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L2261
Product name
Lanatoside C
Purity
≥95%
Packaging
100mg
Price
$145
Updated
2024/03/01
Sigma-Aldrich
Product number
L2261
Product name
Lanatoside C
Purity
≥95%
Packaging
1g
Price
$844
Updated
2024/03/01
TRC
Product number
L173800
Product name
Lanatoside C
Packaging
1mg
Price
$60
Updated
2021/12/16
Usbiological
Product number
297329
Product name
Lanatoside C
Packaging
100mg
Price
$375
Updated
2021/12/16
TRC
Product number
L173800
Product name
Lanatoside C
Packaging
100mg
Price
$410
Updated
2021/12/16
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LANATOSIDE C Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Lanatozid C,Biofarm

Uses

anti-acne

Uses

Glycosides

Manufacturing Process

2000 parts of dry leaves of digitalis lanata are finely ground with 500 parts of sodium chloride, they are then wetted with 1000 parts of water and extracted with 30,000 parts of chloroform. The filtered extract is completely evaporated in vacuum at a low temperature and to the remaining residue are added 1000 parts of dry ether and the whole mixture is left under the ether until the thick viscous mass has been transformed into a hard body. The ether is then poured away and the residue is digested with 1000 parts of ether for about 2 hours under a reflux condenser. After cooling down the mixture, it is filtered, and the residue obtained, which is now in form of a brittle mass, which is then dried in vacuum in order to completely eliminate the remaining ether present, and pulverized. The pulverized mass is advantageously subjected once more to the treatment with ether. The yellow greenish powder thus obtained is then dissolved in 1000 parts of methyl alcohol and to the solution, so obtained a fine suspension of 30 parts lead hydroxide in 1000 parts water is added with stirring. The solution obtained is neutralized, stirred for about 2 hours, andfiltered, and the clear yellowish filtrate is preferably treated again with a small quantity of tannin precipitating substance. The clear filtrate thus obtained is concentrated in vacuum at a low temperature to about 200 parts, whereby the difficultly soluble portion of the glucoside mixture precipitates. The solution is then filtered. The precipitate is dissolved in a small quantity of methyl alcohol and is treated with a small quantity of water whereby the new product begins to precipitate in a crystalline form. By repeated crystallization from methyl alcohol, without addition of water, the glucoside may be obtained in the form of a perfectly pure compound; it does not change its properties even on further recrystallization. The glucoside, freshly crystallized from methyl alcohol and dried in vacuo, had MP: 248°C with decomposition, when heated rapidly. At 230°-235°C, the substance begins to sinter and becomes quite soft; the melting point, therefore, is not well defined.

Therapeutic Function

Cardiotonic

Purification Methods

Crystallise lanatoside C from MeOH. Its solubility is : 1/17000 (H2O), 1/45 (EtOH) and 1/1500-2000 (CHCl3). [Stoll et al. Helv Chim Acta 16 1049 1933, Stoll & Kreis Helv Chim Acta 35 1318 1952, Okada et al. Chem Pharm Bull Jpn 23 2039 1975, Beilstein 18 III/IV 2455.] It is cardiotonic.

LANATOSIDE C Preparation Products And Raw materials

Raw materials

Preparation Products

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LANATOSIDE C Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
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View Lastest Price from LANATOSIDE C manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
LANATOSIDE C 17575-22-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-25
Shanghai Standard Technology Co., Ltd.
Product
Lanatoside C 17575-22-3
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-26
Career Henan Chemical Co
Product
LANATOSIDE C 17575-22-3
Price
US $1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-24

17575-22-3, LANATOSIDE CRelated Search:


  • LANATOSIDE C
  • 20(22),5BETA-CARDENOLID-3BETA,12BETA,14BETA-TRIOL 3BETA-O-BETA-D-GLUCOPYRANOSYL-(1->4)-O-BETA-D-[3-O-ACETYLDIGITOXOPYRANOSYL]-(1->4)-O-BETA-D-DIGITOXOPYRANOSIDE-(1->4)-O-BETA-D-DIGITOXOPYRANOSIDE
  • Lanatoside C (Digoxin Impurity H)
  • cedilanid
  • digilanidc
  • digilanidec
  • Digoxin EP Impurity H
  • Digoxin Impurity 8(Digoxin EP Impurity H)
  • isolanid
  • isolanide
  • Allocor
  • Card-20(22)-enolide, 3-[(O-b-D-glucopyranosyl-(14)-O-3-O-acetyl-2,6-dideoxy-b-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-b-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3b,5b,12b)- (9CI)
  • Ceglunat
  • Ceglunate
  • Celadigal
  • Celanid
  • Celanide
  • Cetosanol
  • Digilanogen C
  • Lanatigen C
  • Lanimerck
  • NSC 119991
  • NSC 7533
  • Lanatosid C
  • LANATOSIDE C 97%
  • LANATOSIDE C WHO(CRM STANDARD)
  • LANATOSIDE C(REAGENT / STANDARD GRADE)
  • Card-20(22)-enolide, 3-[(o-.beta.-D-glucopyranosyl-(1.fwdarw.4)-o-3-o-acetyl-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1.fwdarw.4)-o-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1.fwdarw.4)-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3.beta.,5.beta.,12.beta.)-
  • (3β,5β,12β)-
  • Trigonin C (digoxin impurity H)
  • Digoxin EP Impurity H (Lanatoside C)
  • Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
  • LANATOSIDE C USP/EP/BP
  • Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
  • (2R,3R,4S,6S)-6-(((2R,3S,4S,6S)-6-(((2R,3S,4S,6R)-6-(((3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-2-methyl-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl acetate
  • 3β-[(β-D-glucopyranosyl-(1→4)-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12β,14-dihydroxy-5β-card-20(22)-enolide (lanatoside C),
  • Lanatoside C -RM
  • 17575-22-3
  • C49H76O20
  • Biochemicals and Reagents
  • BioChemical
  • Carbohydrates
  • Oligosaccharide
  • Cardioglycosides & Glycosides
  • Carbohydrates
  • Carbohydrates A to
  • Carbohydrates H-LBiochemicals and Reagents
  • Oligosaccharide
  • Intermediates & Fine Chemicals
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