Diltiazem impurity

Product Name: Diltiazem impurity
CAS No.: 115992-91-1
Chemical Name: Diltiazem impurity
Synonyms: Diltiazem Impurity H;Diltiazem EP Impurity H;diltiazem related compound H;Diltiazem Impurity 8(Diltiazem EP Impurity H);Diltiazem Impurity H (N,N,O-Tridesmethyl Desacetyl Diltiazem);(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one;Diltiazem EP Impurity H/ Diltiazem Related Compound H (N,N,O-Tri-Desmethyl Desacetyl Diltiazem);1,5-Benzothiazepin-4(5H)-one, 5-(2-aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-, (2S,3S)-;(2S,3S)-2-hydroxy-3-(4-methoxyphenyl)-3-[2-(β-N,N-dimethylaminoethylamino)phenylthio]propionic acid;(2S,3S)-5-(2-aminoethyl)-3-hydroxy-2-(4-hydroxyphenyl)-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-4-one
CBNumber: CB33033112
Molecular Formula: C17H18N2O3S
Formula Weight: 330.4
MOL File: 115992-91-1.mol

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Diltiazem impurity Property

Melting point:: 121 - 128°C
Boiling point:: 648.4±55.0 °C(Predicted)
Density: 1.365±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 9.81±0.30(Predicted)
color: White to Light Yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A609220
Product name: (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
Packaging: 10mg
Price: $150
Updated: 2021/12/16

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Diltiazem impurity Chemical Properties,Usage,Production

Uses

(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV).

Diltiazem impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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115992-91-1, Diltiazem impurityRelated Search:

Diltiazem hydrochloride DESACETYL DILTIAZEM HCL Diltiazem N-Oxide O-Desmethyl Diltiazem Hydrochloride diltiazem hydrochloride Diltiazem Impurity 8 Deacetyl-O-demethyl Diltiazem Hydrochloride (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Diltiazem Impurity 4 Diltiazem Impurity 5 Deacetyl Diltiazem N-Oxide N,N,O-Tridesmethyl Diltiazem Desacetyl DiltiazeM-d4 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-trans)- (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride brinzolamide N,N-Didesmethyl Diltiazem Hydrochloride Diltiazem EP Impurity C

(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one

Diltiazem EP Impurity H

Diltiazem Impurity 8(Diltiazem EP Impurity H)

Diltiazem Impurity H

Diltiazem Impurity H (N,N,O-Tridesmethyl Desacetyl Diltiazem)

(2S,3S)-2-hydroxy-3-(4-methoxyphenyl)-3-[2-(β-N,N-dimethylaminoethylamino)phenylthio]propionic acid

Diltiazem EP Impurity H/ Diltiazem Related Compound H (N,N,O-Tri-Desmethyl Desacetyl Diltiazem)

diltiazem related compound H

1,5-Benzothiazepin-4(5H)-one, 5-(2-aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-, (2S,3S)-

(2S,3S)-5-(2-aminoethyl)-3-hydroxy-2-(4-hydroxyphenyl)-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-4-one

115992-91-1