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Diltiazem impurity

Product Name
Diltiazem impurity
CAS No.
115992-91-1
Chemical Name
Diltiazem impurity
Synonyms
Diltiazem Impurity H;Diltiazem EP Impurity H;Diltiazem Impurity H HCl;diltiazem related compound H;Diltiazem Impurity 8(Diltiazem EP Impurity H);Diltiazem Impurity H (N,N,O-Tridesmethyl Desacetyl Diltiazem);(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one;Diltiazem EP Impurity H/ Diltiazem Related Compound H (N,N,O-Tri-Desmethyl Desacetyl Diltiazem);1,5-Benzothiazepin-4(5H)-one, 5-(2-aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-, (2S,3S)-;(2S,3S)-2-hydroxy-3-(4-methoxyphenyl)-3-[2-(β-N,N-dimethylaminoethylamino)phenylthio]propionic acid
CBNumber
CB33033112
Molecular Formula
C17H18N2O3S
Formula Weight
330.4
MOL File
115992-91-1.mol
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Diltiazem impurity Property

Melting point:
121 - 128°C
Boiling point:
648.4±55.0 °C(Predicted)
Density 
1.365±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
9.81±0.30(Predicted)
color 
White to Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A609220
Product name
(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
Packaging
10mg
Price
$150
Updated
2021/12/16
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Diltiazem impurity Chemical Properties,Usage,Production

Uses

(2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one is an impurity of diltiazem (D460620). Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class IV).

Diltiazem impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Diltiazem impurity Suppliers

China 37 India 4 United States 3 Global 44
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
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Fax
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Email
mktg@pharmaffiliates.com
Country
India
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6739
Advantage
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115992-91-1, Diltiazem impurityRelated Search:

Diltiazem hydrochloride DESACETYL DILTIAZEM HCL Diltiazem N-Oxide O-Desmethyl Diltiazem Hydrochloride diltiazem hydrochloride Diltiazem Impurity 8 Deacetyl-O-demethyl Diltiazem Hydrochloride (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Diltiazem Impurity 4 Diltiazem Impurity 5 Deacetyl Diltiazem N-Oxide N,N,O-Tridesmethyl Diltiazem Desacetyl DiltiazeM-d4 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-trans)- (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride brinzolamide N,N-Didesmethyl Diltiazem Hydrochloride Diltiazem EP Impurity C

  • (2S,3S)-5-(2-Aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-1,5-benzothiazepin-4(5H)-one
  • Diltiazem EP Impurity H
  • Diltiazem Impurity 8(Diltiazem EP Impurity H)
  • Diltiazem Impurity H
  • Diltiazem Impurity H (N,N,O-Tridesmethyl Desacetyl Diltiazem)
  • (2S,3S)-2-hydroxy-3-(4-methoxyphenyl)-3-[2-(β-N,N-dimethylaminoethylamino)phenylthio]propionic acid
  • Diltiazem EP Impurity H/ Diltiazem Related Compound H (N,N,O-Tri-Desmethyl Desacetyl Diltiazem)
  • diltiazem related compound H
  • 1,5-Benzothiazepin-4(5H)-one, 5-(2-aminoethyl)-2,3-dihydro-3-hydroxy-2-(4-hydroxyphenyl)-, (2S,3S)-
  • (2S,3S)-5-(2-aminoethyl)-3-hydroxy-2-(4-hydroxyphenyl)-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-4-one
  • Diltiazem Impurity H HCl
  • 115992-91-1