ChemicalBook > CAS DataBase List > 1-OLEOYL-2-ACETYL-SN-GLYCEROL

1-OLEOYL-2-ACETYL-SN-GLYCEROL

Product Name
1-OLEOYL-2-ACETYL-SN-GLYCEROL
CAS No.
86390-77-4
Chemical Name
1-OLEOYL-2-ACETYL-SN-GLYCEROL
Synonyms
OAG;Oleoylacetylglycerol;DG(18:1(9Z)/2:0/0:0);1-Oleyl-2-acetylglycerol;(OAG) oleyl-acetyl glycerol;Sn-1-oleoyl-2-acetylglycerol;1-Olein-2-acetyl-sn-glycerol;1-OLEOYL-2-ACETYL-SN-GLYCEROL;2-ACETYL-1-OLEOYL-SN-GLYCEROL;1-o-Octadecenoyl-2-o-acetylglycerol
CBNumber
CB3303463
Molecular Formula
C23H42O5
Formula Weight
398.58
MOL File
86390-77-4.mol
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1-OLEOYL-2-ACETYL-SN-GLYCEROL Property

Boiling point:
490.0±15.0 °C(Predicted)
Density 
0.980±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
ethanol: 20 mg/mL
form 
oil
pka
13.89±0.10(Predicted)
color 
yellow
BRN 
8168731
Stability:
Temperature Sensitive. This compound can rearrange to the 1,3-isomer in solution or during prolonged storage.
CAS DataBase Reference
86390-77-4(CAS DataBase Reference)
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Safety

WGK Germany 
3
10-23
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
O6754
Product name
1-Oleoyl-2-acetyl-sn-glycerol
Purity
≥97% (TLC), oil
Packaging
5mg
Price
$179
Updated
2024/03/01
Sigma-Aldrich
Product number
O6754
Product name
1-Oleoyl-2-acetyl-sn-glycerol
Purity
≥97% (TLC), oil
Packaging
10mg
Price
$288
Updated
2024/03/01
Sigma-Aldrich
Product number
495414
Product name
1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem
Purity
Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C.
Packaging
5mg
Price
$96.7
Updated
2024/03/01
Sigma-Aldrich
Product number
495414
Product name
1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem
Purity
Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C.
Packaging
25mg
Price
$322
Updated
2024/03/01
Cayman Chemical
Product number
62600
Product name
1-Oleoyl-2-acetyl-sn-glycerol
Purity
≥95%
Packaging
5 mg
Price
$57
Updated
2024/03/01
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1-OLEOYL-2-ACETYL-SN-GLYCEROL Chemical Properties,Usage,Production

Chemical Properties

Colourless to light yellow oil

Uses

Activator of phospholipid-dependent protein kinase C; and stimulator of secretion and aggregation in blood platelets.x

Uses

18:1-2:0 DG (1-oleoyl-2-acetyl-sn-glycerol) has been used as a diacyl glycerol (DAG) analog to test its impact on DAG-sensitive channels in thalamocortical (TC) neurons. It may be used as an internal standard for retention time calibration in ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF MS)?for blood sample lipid quantification. It may also be used as a protein kinase C (PKC) activator in adrenal glands.

Definition

ChEBI: 1-Oleoyl-2-acetyl-sn-glycerol is a 1,2-diglyceride.

General Description

18:1-2:0 DG, also called 1-oleoyl-2-acetyl-sn-glycerol (OADG), is a synthetic analog of diacyl glycerol (DAG) and is membrane permeable.

Biochem/physiol Actions

1-Oleoyl-2-acetyl-sn-glycerol is a synthetic, cell permeable diacylglycerol analog. It is often used as an activator of calcium-dependent protein kinase C (PKC).

1-OLEOYL-2-ACETYL-SN-GLYCEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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86390-77-4, 1-OLEOYL-2-ACETYL-SN-GLYCEROLRelated Search:


  • 1-[CIS-9-OCTADECENOYL]-2-ACETYL-SN-GLYCEROL
  • 2-ACETYL-1-OLEOYL-SN-GLYCEROL
  • 1-OLEOYL-2-ACETYL-SN-GLYCEROL
  • 1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem
  • 1-O-9Z-OCTADECENOYL-2-O-ACETYL-SN-GLYCEROL
  • 1-(cis-9-Octadecenoyl)-2-acetyl-sn-glycerol, 2-Acetyl-1-oleoyl-sn-glycerol, OAG
  • 1-Oleyl-2-acetylglycerol
  • 1-o-Octadecenoyl-2-o-acetylglycerol
  • 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester
  • 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)-
  • Oleoylacetylglycerol
  • Sn-1-oleoyl-2-acetylglycerol
  • (9Z)-9-Octadecenoic Acid 2-(Acetyloxy)-3-hydroxypropyl Ester
  • (S)-2-acetoxy-3-hydroxypropyl oleate
  • OAG
  • (9Z)-9-Octadecenoic acid (2S)-2-(acetyloxy)-3-hydroxypropyl ester
  • DG(18:1(9Z)/2:0/0:0)
  • 1-Oleoyl-2-acetyl-sn-glycerol (OAG)
  • (OAG) oleyl-acetyl glycerol
  • 1-Olein-2-acetyl-sn-glycerol
  • 86390-77-4
  • Lipids
  • Neutral Glycerides
  • Glycerides
  • Diradylglycerols
  • BioChemical
  • Biochemicals and Reagents
  • Chemical Activators
  • Activators
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Protein Kinase Inhibitors and Activators