BHPI

Product Name: BHPI
CAS No.: 56632-39-4
Chemical Name: BHPI
Synonyms: BHPI;CS-2134;1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-
CBNumber: CB33041388
Molecular Formula: C21H17NO3
Formula Weight: 331.36
MOL File: 56632-39-4.mol

More

Less

BHPI Property

Melting point:: 272-274 °C
Boiling point:: 557.7±50.0 °C(Predicted)
Density: 1.320±0.06 g/cm3(Predicted)
solubility: DMF: 5 mg/ml; DMSO: 11 mg/ml; Ethanol: 14 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form: A crystalline solid
pka: 9.43±0.30(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 17750
Product name: BHPI
Purity: ≥95%
Packaging: 500μg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 17750
Product name: BHPI
Purity: ≥95%
Packaging: 1mg
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 17750
Product name: BHPI
Purity: ≥95%
Packaging: 5mg
Price: $412
Updated: 2024/03/01

Tocris

Product number: 6116
Product name: BHPI
Purity: ≥98%(HPLC)
Packaging: 50
Price: $745
Updated: 2021/12/16

Tocris

Product number: 6116
Product name: BHPI
Purity: ≥98%(HPLC)
Packaging: 10
Price: $177
Updated: 2021/12/16

More

Less

BHPI Chemical Properties,Usage,Production

Description

BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial, and ovarian cancer cell lines at concentrations ranging from 10 to 1,000 nM. It is effective in vivo, driving tumor regression in mice bearing MCF-7 xenografts at a dose of 15 mg/kg daily. BHPI specifically inhibits ERα-dependent gene expression and protein synthesis by activating the unfolded protein response in cells.

Uses

BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial and ovarian cancer cell lines.

storage

Store at -20°C

BHPI Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BHPI Suppliers

China 39 United Kingdom 1 United States 8 Global 48

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15085
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9414
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

56632-39-4, BHPIRelated Search:

BHPI

2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-

1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one

CS-2134

56632-39-4