ChemicalBook > CAS DataBase List > SCR-1481B1

SCR-1481B1

Product Name
SCR-1481B1
CAS No.
1174161-86-4
Chemical Name
SCR-1481B1
Synonyms
SCR-1481B1;BMS-817378(tris);c-Met inhibitor 2;SCR-1481B1, 10 mM in DMSO;QPFPEXKJGICONN-UHFFFAOYSA-N;SCR-1481B1(BMS-817378 tris salt);SCR1481B1;BMS-817378;BMS817378;BMS 817378;N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-4-oxo-1-[(phosphonooxy)methyl]- (Tris salt);c-Met/HGFR,Vascular endothelial growth factor receptor,SCR 1481B1,VEGFR,SCR-1481B-1,SCR1481B1,Inhibitor,inhibit,SCR-1481B1;2-Amino-2-(hydroxymethyl)propane-1,3-diol (3-((4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)carbamoyl)-5-(4-fluorophenyl)-4-oxopyridin-1(4H)-yl)methyl phosphate
CBNumber
CB33051750
Molecular Formula
C28H29ClF2N5O10P
Formula Weight
699.99
MOL File
1174161-86-4.mol
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SCR-1481B1 Property

storage temp. 
Store at -20°C
solubility 
DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:8): 0.11 mg/ml; PBS (pH 7.2): slightly soluble
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-5577
Product name
SCR-1481B1
Purity
99.99%
Packaging
5mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-5577
Product name
SCR-1481B1
Purity
99.99%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-5577
Product name
SCR-1481B1
Purity
99.99%
Packaging
50mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-5577
Product name
SCR-1481B1
Purity
99.99%
Packaging
100mg
Price
$750
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573248
Product name
SCR-1481B1(BMS-817378 tris salt)
Purity
>98%
Packaging
100mg
Price
$1133.9
Updated
2021/12/16
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SCR-1481B1 Chemical Properties,Usage,Production

Uses

SCR-1481B1 (Metatinib anhydrous) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.

IC 50

VEGFR1

References

[1] Robert M. Borzilleri, et al. 4-pyridinone compounds and their use for cancer. WO/2009094417/A1.

SCR-1481B1 Preparation Products And Raw materials

Raw materials

Preparation Products

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SCR-1481B1 Suppliers

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1174161-86-4, SCR-1481B1Related Search:

Fluoxetine Sunitinib Lapatinib Imatinib ERDAFITINIB Neratinib Anlotinib Apatinib

  • c-Met inhibitor 2
  • QPFPEXKJGICONN-UHFFFAOYSA-N
  • SCR-1481B1
  • SCR1481B1;BMS-817378;BMS817378;BMS 817378
  • SCR-1481B1(BMS-817378 tris salt)
  • N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-4-oxo-1-[(phosphonooxy)methyl]- (Tris salt)
  • BMS-817378(tris)
  • c-Met/HGFR,Vascular endothelial growth factor receptor,SCR 1481B1,VEGFR,SCR-1481B-1,SCR1481B1,Inhibitor,inhibit,SCR-1481B1
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol (3-((4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)carbamoyl)-5-(4-fluorophenyl)-4-oxopyridin-1(4H)-yl)methyl phosphate
  • SCR-1481B1, 10 mM in DMSO
  • 1174161-86-4